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biology, genome editing, viral and non-viral vector design, cell engineering, and the development of in vitro and in vivo tumor models for cell and gene therapy applications. Furthermore, CellAction
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/ Responsibilities Develop and optimize manufacturing processes for cell and gene therapies, including viral/non-viral vectors and genome editing. Transfer pre-GMP processes into robust, reproducible workflows
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calcium imaging and optogenetics, as well as genome editing and behavioural phenotyping. Where to apply Website https://emploi.cnrs.fr/Offres/Doctorant/UMR7009-FREBON-053/Default.aspx Requirements Research
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characterize cellular and mouse models of TFE3-driven kidney cancer. - Perform molecular biology, genome editing and protein biochemistry experiments. - Study transcription factor regulation, chromatin
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module to limit exhaustion, gene editing (Crispr/Cas9, knocking…) includind in vivo CAR-T. We will also investigate new adoptive cell transfer in solid tumors using TRM or transgenic TCR (please see more