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parasites are transmitted between humans by mosquitoes. In the mosquito host, they undergo an obligate stage of sexual recombination. Transmission-dependent rates of out-crossing, inbreeding, and self
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culture, is also expected. Proficiency in molecular cloning and the generation of recombinant plasmids would further strengthen the candidate's profile. Experience with optical microscopy techniques
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motifs; - establish, optimize, and apply quantitative protein-interaction assays; - perform mammalian cell culture, molecular cloning, mutational analysis, recombinant protein work, and fluorescence
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immunotherapy interventions targeting CD4+ T cells based on recombinant monoclonal antibodies or mRNA-containing lipid nanoparticles. The project will be primarily developed in a pre-clinical murine model of lung
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. The postdoctoral researcher will take a leading role in addressing these questions using complementary molecular, cellular and structural approaches. The work will include recombinant protein production, structural