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microbiology, bacterial genetics, CRISPRi approaches, and bioinformatics analyses to identify the molecular and genetic determinants underlying strain-to-strain differences in stress responses. In particular
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silylated peptides and the Reches group in peptide self-assembly and biomaterials. It would lead to novel robust peptide-based biomaterials that can provide cues to mammalian cells and prevent bacterial
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of the Bacterial Cell Wall Unit headed by Ivo G. Boneca. This is a collaborative project with the teams of Raquel Mejias-Luque of the Technical University of Munich and of Richard Ferrero of the Monash University
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of this important bacterial pathogen. Project Overview: Leptospirosis is a re-emerging zoonotic disease of increasing public health concern, a situation further exacerbated by climate change. Leptospira interrogans
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used by Yersinia pestis to infect fleas. The project will combine bacterial genetics, molecular microbiology, flea infection models and omics-based approaches to identify bacterial determinants required