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Hematopoietic stem cells (HSCs) ensure the lifelong production of all blood cell types. With age, HSCs undergo functional and molecular changes that impair their regenerative capacity and contribute
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the Lipid Trafficking and Membrane Contact Sites team at the Institute for Integrative Biology of the Cell (I2BC, Université Paris-Saclay), under the supervision of Francesca Giordano and co-supervision
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(NK) cells are central effectors of anti-tumor immunity in the liver, yet their function is strongly inhibited by TGFβ signaling during tumor progression. Recent discoveries suggest that Notch signaling
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upon endocrine perturbation. Ovaries regulate the production of hormones and oocytes released at ovulation. The ovarian surface epithelium (OSE) plays a central role in homeostasis by repairing ovulation
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cells. Proteomic approaches have identified several surface proteins that are overexpressed in glioblastoma stem cells compared with non-tumour cells, and whose role in glioblastoma biology remains to be
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at the IBDM (Institute of Developmental Biology of Marseille) within the “Physical approaches to cell dynamics and tissue morphogenesis (PoM)” team, and at IUSTI (University Institute of Industrial Thermal
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Requirements Research FieldBiological sciences » BiologyEducation LevelMaster Degree or equivalent Skills/Qualifications Strong background in immunology, cell biology and/or hematology. Experience with mammalian
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Scientific Themes: This PhD project aims to study the response of cancer cells to ionizing radiation in the presence of radio-enhancing metallic nanoparticles. The objective is to characterize
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“Signalling and Cytoskeleton Dynamics” research team at the Cell Biology Research Centre of Montpellier (CRBM). A thesis monitoring committee will be established to oversee the progress of the research through
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(MCU-PH). The PhD student will be co-supervised by Dr Julie Bernardor and Dr Stoyan Ivanov (immunologist, expert in myeloid cell biology), and will more broadly benefit from established collaborations