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Hematopoietic stem cells (HSCs) ensure the lifelong production of all blood cell types. With age, HSCs undergo functional and molecular changes that impair their regenerative capacity and contribute
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the Lipid Trafficking and Membrane Contact Sites team at the Institute for Integrative Biology of the Cell (I2BC, Université Paris-Saclay), under the supervision of Francesca Giordano and co-supervision
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cells. Proteomic approaches have identified several surface proteins that are overexpressed in glioblastoma stem cells compared with non-tumour cells, and whose role in glioblastoma biology remains to be
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nanoassemblies, composed of organic radicals, endowed with photoactive units (fluorescent, photochromic), and strong affinity toward superparamagnetic iron oxide nanoparticles. Particular attention will be paid
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the most promising technologies for the degradation of these recalcitrant pollutants. They enable the in-situ generation of highly reactive oxidizing species without the addition of chemical reagents and can
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neural stem cell (NSC) niche. Recent studies have revealed key aspects of human rhombic lip (hRL) organization and shown that defects in its development underlie several human syndromes. These findings
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advanced cell imaging. The successful candidate will work in a highly interdisciplinary research environment and will have access to state-of-the-art technological platforms, including cleanroom
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, cell biology, and tissue engineering. The project builds upon the complementary expertise of LAAS-CNRS and the RESTORE research center. LAAS-CNRS will provide expertise in microfabrication, microfluidic
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, that appear in solid-state systems of reduced dimensionality or nanometric size, as well as in materials with strong electronic correlations. The goal is to provide innovative solutions to major challenges in
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to medium level skills in programming, image analysis and electronics • Solid knowledge and hands-on experience in light and electron microscopy. • Solid formation in genetics, statistics and molecular