POSTDOC POSITION IN ORGANIC SYNTHESIS AND HOMOGENEOUS CATALYSIS (H/F)

The postdoctoral researcher will be in charge of the:
1/ Synthesis of small functionalized molecules derived from the benzene-1,3,5-tricarboxamide (BTA) scaffold.
2/ Implementation of the functionalized BTA assemblies in asymmetric cooperative catalysis.

The postdoctoral researcher will be in charge of designing a new class of supramolecular cooperative catalysts in the framework of the collaborative ANR AdECat project,

In the framework of the ANR PRC AdECat project, the specific features of our previously developed supramolecular helical scaffold will be exploited for catalytic reactions requiring a dual activation of substrate(s). Towards this goal, we will implement helices composed of different catalytic sites with the aim of improving the efficiency of catalytic reactions, notably through a cooperative activation of the substrate(s). A crucial point is to control the sequence of the monomers in order to favour the interaction between the different catalytic sites. We plan to use a set of complementary monomers functionalized with different chemical groups. The postdoctoral research associate will work conjointly with Matthieu Raynal but will be fully integrated in the multi-partner AdECat project, which involves several academic partners in Paris, Bordeaux and Tarragona. Our team has a strong expertise in the preparation and characterization of hydrogen-bonded supramolecular polymers.

Seelcted references:
(a) M. Raynal, F. Portier, P. W. N. M. van Leeuwen, L. Bouteiller, J. Am. Chem. Soc., 2013, 135, 17687. https://doi.org/10.1021/ja408860s . (b) A. Desmarchelier, X. Caumes, M. Raynal, A. Vidal-Ferran, P. W. N. M. van Leeuwen, L. Bouteiller, J. Am. Chem. Soc., 2016, 138, 4908. https://doi.org/10.1021/jacs.6b01306 . (c) J. M. Zimbron, X. Caumes, Y. Li, C. M. Thomas, M. Raynal, L. Bouteiller, Angew. Chem. Int. Ed., 2017, 56, 14016. https://doi.org/10.1002/anie.201706757 . (d) Y. Li, X. Caumes, M. Raynal, L. Bouteiller, Chem. Commun., 2019, 55, 2162. https://doi.org/10.1039/C8CC09819K . (e) Y. Li, L. Bouteiller, M. Raynal, ChemCatChem, 2019, 11, 5212. DOI : 10.1002/cctc.201901246. (f) Y. Li, A. Hammoud, L. Bouteiller, M. Raynal, J. Am. Chem. Soc., 2020, 142, 5676. https://doi.org/10.1021/jacs.9b13157 . (g) M. Martinez-Aguirre, Y. Li, N. Vanthuyne, L. Bouteiller, M. Raynal, Angew. Chem. Int. Ed., 2021, 60, 4183-4191. https://doi.org/10.1002/anie.202012457 .