PhD scholarship in analysis of clinically important cell-surface…

This project is a multidisciplinary collaboration with University of Gothenburg and Lund University, both in Sweden and aims at developing enzymatic solutions for transformation of clinically important cell surface epitopes.
If you are looking for an opportunity to be a part of an international top notch research team working on solving a major global health challenge, then this is the right project for you.

Responsibilities and qualifications
The overarching aim of you project is to explore the interactions of a suite of enzymes with cell surface glycan structures. Your work will include the preparation of glycans from glycolipids and glycoproteins that decorate the cell surfaces of specific human cells and performing detailed analyses using mass spectrometry approaches to determine the structural variations in these clinically important glycans. This works sets the stage for evaluating how a panel of enzymes that are developed within the project transform specific medicinally important epitopes at the surfaces of these glycans. You will spend significant time at Gothenburg University where you will be trained by our collaboration partners to perform these glycomic analyses at the facilities at the University of Gothenburg. You will also interact with our collaboration partners at Lund University, where the human cells will be collected.
Desired candidate academic and personal profile:

• An outstanding academic record with a strong background in biochemistry is critical, preferably within carbohydrate chemistry and/or glycobiology
• Experience in liquid chromatography tandem mass spectrometry (LC-MS) is a paramount advantage. Skills in protein chemistry, statistics, programming would be great assets
• Hard-working, very motivated, ambitious and aiming for excellence. In addition, you need to be able to work independently, and to thrive in an international collaborative environment, where you will work in at least two different laboratories within the project.

You must have a two-year master’s degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master’s degree.

Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU’s rules for the PhD education .

Assessment
The assessment of Candidates will be made by Prof. Maher Abou Hachem and Prof. Susann Teneberg.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years.
You can read more about career paths at DTU here .

Further information
Further information may be obtained from Professor Maher Abou Hachem, email: [email protected]
You can read more about DTU Bioengineering at https://www.bioengineering.dtu.dk/
If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark . Furthermore, you have the option of joining our monthly free seminar “PhD relocation to Denmark and startup “Zoom” seminar ” for all questions regarding the practical matters of moving to Denmark and working as a PhD at DTU.

Application procedure
Your complete online application must be submitted no later than 1 March 2023(Danish time).
Apply at: PhD scholarship in analysis of clinically important cell-surface glycans and their enzymatic modification in the Protein Glycoscience and Biotechnology group

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply now”, fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

• A letter motivating the application (cover letter)
• Curriculum vitae
• Grade transcripts and BSc/MSc diploma (in English) including official description of grading scale
• Contact details to at least two academic references

You may apply prior to ob­tai­ning your master’s degree but cannot begin before having received it.
Applications received after the deadline will not be considered.
All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

The Department of Biotechnology and Biomedicine (DTU Bioengineering) is an international leader in the areas of biotechnology and biomedicine. Our engineering approach to all aspects of biotechnology and biomedicine positions us as a valuable player with unique competences in a growing bio-based economy and with health systems transforming towards personalized medicine. We have a clear focus on the needs in the life science industry and point towards innovation, new businesses, and scientific services for the benefit of society. The department has extensive collaborations with national and international research units and industry. DTU Bioengineering has approx. 400 employees, of which 2/3 are scientific staff. The department is located at DTU Lyngby Campus.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,400 students and 5,800 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.