The KIOS Center of Excellence and the Department of Electrical and Computer Engineering at the University of Cyprus (UCY), announce one vacancy for a full-time Ph.D. position (under the Special Scientist category), funded under the European Horizon 2020 project “GLADIATOR - Next-generation theranostics of brain pathologies with autonomous externally controllable nanonetworks: a trans-disciplinary approach with bio-nanodevice interfaces”. The GLADIATOR project is a Horizon 2020 FETOPEN project that involves 6 leading academic institutions (University of Cyprus, University of Oulu, Fraunhofer Institute for Biomedical Engineering, Waterford Institute of Technology, Norwegian University of Science and Technology, and Osaka University) and EPOSIasis, a vibrant nano-biotechnology SME. The ideal candidate will have a master’s degree with specialization in photonics, preferably for biomedical applications. Additional expertise in microelectronics and/or microwave engineering is desirable (but not essential).
The aim of this Ph.D. position is to develop brain micro-implants that incorporate optoelectronics for fluorescence detection, within the framework of the GLADIATOR FET-OPEN project. GLADIATOR targets the creation of a theranostic (therapeutic + diagnostic) system for the diagnosis and treatment of brain cancer, consisting of a headwearable patch for power transfer and communication with a multimodal (RF, photonic and ultrasound) microimplant. GLADIATOR will produce a working prototype of a complete, autonomous, clinically-applicable, nanonetwork-based molecular communications system based on externally controllable molecular communications (ECMC). That is, through breakthroughs in both cell biology and RF and photonic devices, the system will both monitor and treat brain tumours. The system will consist of a hybrid bio-electronic interface with coupled external and implantable devices, which will establish communication channels with host-derived fluorescent reporter cells via micro-optoelectronic sensors. The cellular, sub-cellular and electronic components will be integrated into a wireless ECMC system residing on the patient’s brain. The system will autonomously monitor the spatiotemporal tumour evolution and recurrence, and will generate on demand appropriate reprogramming interventions by stimulating the engineered stem cells.
DUTIES AND RESPONSIBILITIES:
- Development of a prototype hybrid brain micro-implant, including optoelectronics for fluorescence detection and heterogeneous integration with the associated drive electronics, transcranial power transfer and transcranial communications. The implemented solution is likely to require a multichip module approach, with development of photonic hybrid integrated circuits as part of this.
- Close interaction and collaboration with other researchers in the GLADIATOR consortium, including reporting to the project coordinator as appropriate.
- Collaborating and supporting the local team at UCY towards the implementation of research objectives
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