PhD position: regeneration of locomotor circuits after spinal cord injury in salamanders

Updated: 3 months ago
Location: Sherbrooke East, QUEBEC
Job Type: FullTime
Deadline: 14 Mar 2024

6 Feb 2024
Job Information
Organisation/Company

Université de Sherbrooke
Research Field

Psychological sciences » Psychology
Researcher Profile

Recognised Researcher (R2)
Leading Researcher (R4)
First Stage Researcher (R1)
Established Researcher (R3)
Country

Canada
Application Deadline

14 Mar 2024 - 22:00 (UTC)
Type of Contract

Temporary
Job Status

Full-time
Offer Starting Date

2 Sep 2024
Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

In mammals, voluntary locomotion is lost after full transection of the spinal cord. In salamanders, the spinal cord regenerates and the animal recovers voluntary locomotion after a few weeks. How this occurs is largely unknown. Genetic dissection of salamander neural circuits is now feasible with methods for manipulation, elimination, and visualisation of cells. Such approaches can be combined with neuroscience tools such as calcium imaging (confocal and two-photon imaging), patch-clamp electrophysiology, optogenetics, tracing and movement analysis (for review see Ryczko et al. 2020 Trends in Neurosciences, 43(11):916-930, https://doi.org/10.1016/j.tins.2020.08.006 ). The candidate will use these powerful approaches to dissect the organisation of salamander locomotor circuits in the intact and regenerated spinal cord. The present ERC synergy grant project will be carried out in close collaboration with modelers and roboticists who are building a detailed model of the salamander circuits (team of Pr. Auke Ijspeert, EPFL, Lausanne, Switzerland) and experts in genomics and regeneration who generate transgenic salamanders (team of Pr. Andras Simon, Karolinska Institute, Stockholm, Sweden).

Funding category: Financement public/privé
European Research Council
PHD title: Doctorat en Physiologie
PHD Country: Canada


Requirements
Specific Requirements

REQUIREMENTS: The candidate should have obtained a master's degree in neuroscience or an equivalent field. An asset for the candidate would be to have experience in electrophysiology or calcium imaging, optogenetics, or movement analysis, and a keen interest in motor control.


Additional Information
Work Location(s)
Number of offers available
1
Company/Institute
Université de Sherbrooke
Country
Canada
City
Sherbrooke
Geofield


Where to apply
Website

https://www.abg.asso.fr/fr/candidatOffres/show/id_offre/119974

Contact
Website

https://ryczkolab.wordpress.com/

STATUS: EXPIRED