6 Feb 2024
Job Information
- Organisation/Company
Université de Sherbrooke- Research Field
Psychological sciences » Psychology- Researcher Profile
Recognised Researcher (R2)
Leading Researcher (R4)
First Stage Researcher (R1)
Established Researcher (R3)- Country
Canada- Application Deadline
14 Mar 2024 - 22:00 (UTC)- Type of Contract
Temporary- Job Status
Full-time- Offer Starting Date
2 Sep 2024- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
The locomotor role of dopaminergic cells is classically attributed to their ascending projections to the basal ganglia that project to the Mesencephalic Locomotor Region (MLR), a brainstem region that controls locomotion. However, descending projections to the MLR were uncovered (Ryczko et al. PNAS 2013, PNAS 2016, J Neurosci 2017, J Neurosci 2020). In lamprey, this descending pathway increases locomotor activity. In mammals, the role of such innervation remains to be determined.
The student will address this issue using patch-clamp electrophysiology and optogenetics in brain slices, calcium imaging, viral tracing, in vivo optogenetics and movement analysis in mice. The new knowledge will provide a better understanding of the relation between dopaminergic and locomotor neurons and help identify new clinical strategies to improve locomotor function in Parkinson’s disease.
Funding category: Financement public/privé
Canadian Institute for Health Research
PHD title: Doctorat en Physiologie
PHD Country: Canada
Requirements
Specific Requirements
REQUIREMENTS: The candidate should have obtained a master's degree in neuroscience or a related field. An asset for the candidate would be to have experience in electrophysiology or calcium imaging, optogenetics, and a keen interest in motor control.
Additional Information
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Université de Sherbrooke
- Country
- Canada
- City
- Sherbrooke
- Geofield
Where to apply
- Website
https://www.abg.asso.fr/fr/candidatOffres/show/id_offre/119973
Contact
- Website
https://ryczkolab.wordpress.com/
STATUS: EXPIRED