PhD student in the Mechanistic Molecular Biology group

(ref. BAP-2021-575)

Laatst aangepast : 8/07/2021

The PhD student will be hosted in the Mechanistic Molecular Biology group headed by prof Shehab Ismail within the Biochemistry, Molecular and Structural Biology unit at the Chemistry department.

Project

Members of the Ras superfamily of small G-proteins are involved in regulating almost all human cellular processes. With twenty members, Arl proteins comprise the largest group of the Arf family of small G-proteins. Arl proteins have been implicated in diseases and their depletion causes dramatic changes in cell physiology, but their function and regulation remains largely obscure. The PhD student will be part of a team that use biochemistry, structural biology and cell biology approaches to illuminate the function of this crucial but still understudied protein family.  

Examples of past relevant work 

https://doi.org/10.1038/ncomms11366

https://doi.org/10.1016/j.devcel.2018.08.012

https://doi.org/10.1016/j.ajhg.2018.08.015

https://doi.org/10.7554/elife.64624

Profile

We are seeking highly motivated candidates that hold a master’s degree in  biochemistry, chemistry, biotechnology or biology or related subjects. Prior knowledge of structural biology, biochemical assays or cell biology approaches is a plus.

Offer

• We offer a PhD fellowship in Biochemistry.
• The fellowship is for 1 year but can be extended after a positive evaluation. 
• Work in a multidisciplinary environment and collaborating nationally and internationally.
• Possibilities for further doctoral training for PhD candidates is provided in the framework of the KU Leuven Arenberg Doctoral School (https://set.kuleuven.be/phd) and by the Doctoral School of Biomedical Sciences (https://gbiomed.kuleuven.be/english/phd).

Interested?

For more information please contact Prof. dr. Shehab Ismail, tel.: +32 16 19 48 51, mail: [email protected] or Mr. Raf Goossens, tel.: +32 16 32 04 40, mail: [email protected].

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