The Faculteit Geneeskunde en Farmacie, Department Basis (bio)-medische wetenschappen, is looking for a PhD-student with a doctoral grant.
More concretely your work package, for the preparation of a doctorate, contains:
PhD research on the intitiation of liver fibrosis, as a member of the Liver Cell Biology research group of Prof. Leo van Grunsven, Brussels Health Campus of the VUB (Jette).
The lab studies molecular mechanism involved in liver disease and liver regeneration, thereby making use of several mouse models as well as in vitro models of liver disease (for more information please visit https://livr.research.vub.be/). The general aim of the PhD project is to increase our understanding of the initiating events of hepatic stellate cell activation that take place when a liver is damaged due to an acute or even a chronic liver insult. The project is based on the central hypothesis that quiescent HSCs quickly respond to injury by driving the transcription of only a limited set of genes that result in the final scar tissue-forming activated phenotype.
You will study liver fibrosis initiation and hepatic stellate cell activation in mouse livers and in advanced in vitro 3D spheroid cultures.
You will determine the chromatin landscape and dynamics of quiescent, activated and inactivated HSCs.
You will be trained in RNAseq analysis, multicellular 3D tissue culture and all standard RNA and protein techniques.
You’ll have the opportunity to participate in local and international conferences, in order to expand your scientific network.
You will enroll in the Doctoral School of Life Sciences and Medicine to benefit from workshops on domain specific skills as well as transferable skills.
For this function, our Brussels Health Campus (Jette) will serve as your home base.
Similar Positions
-
Ph D Position, The French Alternative Energies and Atomic Energy Commission, or CEA, France, 28 days ago
21 Mar 2024 Job Information Organisation/Company The French Alternative Energies and Atomic Energy Commission, or CEA Research Field Engineering Researcher Profile First Stage Researcher (R1) Coun...
-
Ph D In Gene Therapy, UCLouvain, Belgium, 23 days ago
26 Mar 2024 Job Information Organisation/Company UCLouvain Department Institut de Recherche Expérimentale et Clinique Research Field Medical sciences » Medicine Researcher Profile First Stage Rese...
-
Ph D Student Position In Blood Cancer Research , University of Basel, Switzerland, 14 days ago
The Department of Biomedicine (DBM) is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of he...
-
Ph D Position In Biotechnology, Slovak University of Agriculture in Nitra, Slovakia, 1 day ago
17 Apr 2024 Job Information Organisation/Company Slovak University of Agriculture in Nitra Department Faculty of Biotechnology and Food Science Research Field Agricultural sciences Researcher Prof...
-
Ph D Position In Biotechnology, Slovak University of Agriculture in Nitra, Slovakia, 1 day ago
17 Apr 2024 Job Information Organisation/Company Slovak University of Agriculture in Nitra Department Faculty of Biotechnology and Food Science Research Field Agricultural sciences Researcher Prof...
-
Ph D Scholarship In Applied Stem Cell Cultivation – Dtu Bioengineering, Technical University of Denmark, Denmark, about 6 hours ago
Skip to main content. Profile Sign Out View More Jobs PhD scholarship in Applied Stem Cell Cultivation – DTU Bioengineering Kgs. Lyngby, Denmark Trending Job Description This is a perfect position...