Since over 25 years the Laboratory for Therapeutic and Diagnostic Antibodies focusses on the generation and characterization of monoclonal antibodies (mAbs), antibody derivatives, nanobodies and diabodies and application as either therapeutics, diagnostics or research tools. The current position is to strengthen our research related to nanobody discovery and development. The candidate will be exposed to a multitude of aspects of this research: immunization strategies, cloning of nanobody libraries, phage display, biochemical (AlphaScreen, ELISA, …) and cell based (FACS, reporter assays, …) screening techniques, protein expression in different host systems (E.coli, yeast, mammalian cells, …), protein purification, assay development, in vitro and in vivo characterization, nanobody engineering (affinity maturation, sequence optimization, protein fusions,…), etc. Potential research domains are related to innovative methods to improve antibody-drug conjugates (ADCs) for cancer therapy, developing novel high throughput nanobody/antibody screening methods, exploring new ways to deliver biologics over the blood-brain barrier, target & drug discovery in Alzheimer’s disease, … The exact project will be defined depending on the candidate’s interest and laboratory’s needs.
Ph D Student For Sars Co V 2 Project , University of Zurich, Switzerland, 1 day ago
Institute of Virology Experimental Virology, Vetsuisse Faculty PhD student for SARS-CoV-2 Project 100 % Subject: B. subtilis as a platform for active and passive immunization against SARS-CoV-2 Th...
Ph D Position At The Vorobieva Lab, VIB, Belgium, about 4 hours ago
Ph.D. position – High-throughput in silico design and experimental characterization of membrane proteins About the Lab The laboratory of computational protein design, headed by Dr. Anastassia Voro...
Postdoc Position In Bioinorganic Chemistry With Focus On Copper Proteins, Chalmers University of Technology, Sweden, about 21 hours ago
We are looking for a postdoc with expertise in copper-protein chemistry that will focus on mechanistic research related to putative roles of copper-proteins in cancer and neurodegeneration. The wo...
Doctoral Candidate Plant And Single Cell Protein Processing , ETH Zurich, Switzerland, about 9 hours ago
In der aktuellen Covid-19 Situation laufen die Rekrutierungen weiter. Es kann dabei allerdings zu Verzögerungen kommen. Vielen Dank für Ihr Verständnis. 100%, Zurich, fixed-term The Sustainable Fo...
Postdoc Position In Cancer Cell Biology – Protein Centric Studies Of Cancer Drug Mechanisms Of Action And Resistance (Scholarship), Karolinska Institute, Sweden, 1 day ago
Do you want to contribute to top quality medical research? In spite of major advances in oncology in recent decades, many cancers cannot be controlled with current therapies. Unfortunately, in spi...
Ph D Student Position In Chemical Protein Synthesis , University of Zurich, Switzerland, 1 day ago
Department of Chemistry PhD student position in chemical protein synthesis 60 % A PhD student position is available in the group of Prof. Dr. Nina Hartrampf in the Department of Chemistry at Univer...