Doctoral scholarship holder Computational Neurobiology

Department: Department of Biomedical Sciences
Regime Full-time

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The Department of Biomedical Sciences in the Faculty of Pharmaceutical, Biomedical and Veterinary Sciences is looking for a full-time doctoral scholarship holder in the field of Computational Neurobiology

Position

We are the Computational Neurobiology lab and address fundamental questions in chromatin organization, epigenetics and brain biology. We develop machine learning approaches for large-scale data integration and reconstruct cis-regulatory networks to understand how a cell “chooses” its fate. In particular, we focus on the role of chromatin organization in neuronal cell fate specification and neurodegenerative disease, aiming to bring results of fundamental research to the clinic.

The proposed PhD project aims to understand how a cell makes a choice between gene isoforms with alternative transcription start sites, and in particular, what is the role of chromatin organisation in this process. The selected candidate will work in the context of the human neuro-immune system and will use cutting-edge experimental and computational techniques to reveal the cis-regulatory networks underlying this complex process.

The VIB-UAntwerp Center for Molecular Neurology has 6 PIs and hosts internationally recognized leaders in the field of Neurogenetics and Neuroinflammation. Current research groups address a broad set of questions related to neurodegenerative diseases of the central and peripheral nervous system, with an emphasis on understanding the genetic etiology and developing diagnostics and treatment methods for these diseases. Approaches range from human genetics and genomics to protein biochemistry and neuronal and glial cell biology, while models include yeast, fly, mouse, and pluripotent human cell systems. Research groups have access to state-of-the-art research and top-notch support core facilities and attract talented international scientist from across the world. 

The VIB-UAntwerp Center is part of VIB, a Life Sciences institute with colleague-researchers in cancer, biotechnology, structural biology, immunology amongst others and an extensive set of core facilities and opportunities for technology transfer.

Profile

• You hold a Master degree in Systems Biology, Molecular Biology, Natural Sciences or related disciplines
• You can demonstrate excellent study results.
• Your research qualities are in line with the faculty and university research policies .
• You act with attention to quality, integrity, creativity and cooperation.
• You have good communication and writing skills in English
• You are very motivated and enthusiastic to learn and expand both computational and experimental skill set

Required skills

• confident in basic molecular biology techniques
• basic programming skills in R and/or python

Desirable skills

• knowledge of gene regulatory mechanisms
• statistical analysis
• processing of NGS data

What we offer

• A strong and dynamic network of international collaborators
• A stimulating and international research environment
• Dedicated training programs available through VIB and UAntwerp to broaden your expertise and enhance your skillset
• Access to state-of-the-art infrastructure and core facilities in a vibrant, world-class research environment operating at an international level
• The host lab provides financial support for the whole length of the PhD. The applicant will also be assisted in applying for personal fellowships.
•  Starting date: as soon as possible, can be discussed
•  Your monthly scholarship amount is calculated according to the scholarship amounts  for doctoral scholarship holders on the pay scales for Contract Research Staff (Dutch: Bijzonder Academisch Personeel, BAP).
• You will receive ecocheques, Internet-connectivity allowance and a bicycle allowance or a full reimbursement of public transport costs for commuting.
• Find out more about working at the University of Antwerp here .

Want to apply?

• You can apply for this vacancy through the University of Antwerp’s online job application platform. Click on the 'Apply' button, complete the online application form and be sure to include the following attachments:
  • a detailed CV
  • a letter of motivation describing your interests
  • contact details of one or two referees
• The selection committee will review all of the applications and as soon as a decision has been made, we will inform you about the next steps in the selection procedure.
• If you have any questions about the online application form, please check the frequently asked questions  or send an email to [email protected] . If you have any questions about the job itself, please contact [email protected]  or [email protected]

https://malyshevalab.sites.vib.be/

https://uantwerpen.vib.be/

The University of Antwerp received the European Commission’s HR Excellence in Research Award  for its HR policy. We are a sustainable, family-friendly organisation which invests in its employees’ growth. We encourage diversity  and attach great importance to an inclusive working environment and equal opportunities, regardless of gender identity, disability, race, ethnicity, religion or belief, sexual orientation or age. We encourage people from diverse backgrounds and with diverse characteristics to apply.