PhD Student

The Department of Biosciences of the Paris Lodron University of Salzburg is pleased to announce the following position, employment commence as soon as possible:

PhD student

Project description

The project aims to investigate immunological mechanisms involved in birch-pollen mediated allergic sensitization. The funding is for 3 years via the Austrian Science Fund (FWF).

Tasks

• Fractionation and characterization of pollen extracts
• Isolation and culture of murine/human primary cells from blood (dendritic cells)
• Stimulation of dendritic cells with pollen extracts, fractions of extracts and candidate compounds
• Analysis of the cytokine- and chemokine profile and expression of surface markers (e.g. TLRs)
• Analysis of active signal transduction pathways
• In vivo polarization and sensitization models
• Statistical evaluation of the results
• Identification of cellular response patterns with multivariate statistical methods (PCA, t-SNE)
• Comparison of results from human in vitro experiments with data from mouse experiments
• Drafting of publication(s) and thesis

Your profile/qualifications

• Master or diploma degree in life sciences (e.g. molecular biology, medical biology, biology, biochemistry, etc.)
• Passion for science, intrinsic motivation, creativity and perseverance
• Ability to work independently in a systematic and focused way
• Basic knowledge in standard molecular biology, biochemical, and immunological methods (FACS, ELISA, Western Blot, qPCR)
• Background or theoretical knowledge in immunology
• Interest in immunology and bioinformatics
• Good spoken and written English language skills

Of advantage, but not absolutely required

• Knowledge and experience in cell culture
• Experience in mouse models, evtl. FELASA certificate

What we offer

• an interesting project with high impact in basic science with excellent publication chances
• A stimulating, multi-disciplinary and international working environment
• A modern lab with state-of-the-art technologies

Additional information:

Start: 2022

Duration: 3 years; 30 h/week

The job location is at PLUS, Hellbrunnerstrasse 34, Salzburg, Austria.

The position is limited to 3 years.

People with disabilities or chronic diseases, who fulfil the requirements, are particularly encouraged to apply. Where qualification is equivalent, female candidates will be given preferential consideration.

Do you have further questions about this open position?

Please contact Dr. Lorenz Aglas, Tel. 0043 662 8044 5819

How to apply:

We are looking forward to receiving your full application as PDF (CV max. 2 pages, letter of motivation max. 1 page) until 22nd of December, 2021.

Please address your application to:

[email protected]

We cannot reimburse any costs that may arise from your application.