PhD position in yeast synthetic biology for the production of proteins with unnatural amino acids...

Updated: over 2 years ago
Job Type: FullTime
Deadline: 05 Sep 2021

PhD position

in yeast synthetic biology for the production of proteins with unnatural amino acids in Pichia pastoris

in Vienna / Austria for 30 hours a week

That’s the project

Unnatural amino acids contain side chains with extraordinary chemical and/or structural properties that are unavailable from the standard amino acids. This makes them particularly attractive as building blocks for synthetic proteins and bioactive compounds. We intend to genetically encode unnatural amino acid with a reactive side chain in the methylotrophic yeast Pichia pastoris. This yeast combines easy genetic manipulation and inexpensive growth media with the ability to express and secrete into the medium recombinant proteins with complex post-translational modifications. The project intends to advance this exciting host organism to the next level of recombinant protein production.



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