2023 RTP - Using synthetic biology to build new gene therapies

Updated: almost 2 years ago
Location: Perth, WESTERN AUSTRALIA
Deadline: The position may have been removed or expired!

Status: Open

Applications open: 8/07/2022
Applications close: 18/08/2022

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About this scholarship

The ability to alter the genomes of living cells is key to understanding how genes influence all the functions of organisms and will be critical to modify living systems for useful purposes. However, this has long been limited by the technical challenges involved in genetic engineering. Recent advances in gene editing have bypassed some of these challenges but they are still far from ideal. Our laboratory has established new protein-based therapies that can target single stranded DNA and RNA in a programmable manner, which are now moving towards clinical trials. In this project the successful applicant will build expertise in synthetic biology and capitalize on the established skills in the laboratory of European Inventor Hall of Fame inductee Professor Oliver Rackham to engineer gene editing systems capable of efficient genetic modifications that are not possible with current systems.
Improved gene editing will be vital to basic science laboratories to reveal the genetic basis of molecular, organelle, cellular and organismal function. While in medicine, gene editing is poised to revolutionize pharmaceutical development, xenotransplantation, the development of gene and cell-based therapies, as well as approaches to control of insect-borne diseases and preventing the inheritance of disease-causing mutations. The gene editing approaches developed in this project will be focused on enabling new gene therapies for childhood metabolic and neuromuscular diseases. 

An Internship opportunity may also be available with this project.


  • Future Students

  • Faculty of Health Sciences

  • Higher Degree by Research

  • Australian Citizen
  • Australian Permanent Resident
  • New Zealand Citizen
  • Permanent Humanitarian Visa

  • Merit Based

The annual scholarship package (stipend and tuition fees) is approx. $60,000 - $70,000 p.a.

 

Successful HDR applicants for admission will receive a 100% fee offset for up to 4 years, stipend scholarships, valued at $28,854 p.a. for up to a maximum of 3.5 years, are determined via a competitive selection process. Applicants will be notified of the scholarship outcome in November 2022. 

 

For detailed information, visit: Research Training Program (RTP) Scholarships | Curtin University, Perth, Australia.


Scholarship Details

1


All applicable HDR courses


• Undergraduate degree in Biochemistry, Genetics, Bioinformatics, Molecular Biology, Microbiology or a related discipline
• A passionate student, interested in synthetic biology and the potential of gene editing for health
• Willingness to learn new skills
• Good problem-solving skills
• Ability to work well independently or in a team 


Application process

If this project excites you, and your research skills and experience are a good fit for this specific project, you should contact the Project Lead (listed below in the enquires section) via the Expression of Interest (EOI) form. ahead of the closing date.


Enrolment Requirements

Eligible to enrol in a Higher Degree by Research Course at Curtin University by March 2023


Enquiries

To enquire about this project opportunity that includes a scholarship application, contact the Project lead, Professor Oliver Rackham via the EOI form above.



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