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comparative proteomics and digital transcriptomics, we have already isolated and characterised over twenty potential therapeutic candidate molecules (both proteins and miRNA), all demonstrating qualities
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infection and resolving inflammation. We utilise a range of technologies to develop our understanding of the ontogeny and function of these cells including proteomic, transcriptomic and epigenetic approaches
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of Resveratrol and similar compounds on lifespan and ageing (senescence) markers in Killifish using RNA-seq and proteomic approaches. Once novel pathways are identified, the project will then use gene editing
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advanced bioimaging (including super-resolution, confocal and electron microscopy), genomics, proteomics, metabolomics, high-performance computing and field research. We promote education and research
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of glomerular immune complex disease as well as the establishment of a novel model for IgA Nephropathy. Additionally, you will contribute to spatial transcriptomics and proteomics in human IgAN kidney samples
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spectrometry proteomics data using our in-house developed APEX2-/TurboID peroxidase-directed proximal biotinylation assay. The candidate will analyse our GR interactome proteomics data and identify differential
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also have documented experience in single cell technologies including but not limited to next generation sequencing, spatial transcriptomics or proteomics, or multiplexed imaging such as immune mass
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areas: antifungal immunity; fungal recognition mechanisms; advanced fungal molecular and cell biology and biochemistry; advanced microscopy; genomics and/or proteomics; cytometry. They will have a proven
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in the human and mouse intestine. You will be applying a range of molecular biology techniques (e.g., single cell/spatial transcriptomics & proteomics) to profile patient cohort samples and mouse
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research on appropriate statistical and machine-learning methodology in the areas of large scale omics data such as genomics, transcriptomics, proteomics/metabolomics and the integration of these, as