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Field
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they promote translocation biogenesis, and testing them in preclinical models. The work combines CRISPR engineering of B cells, protein biochemistry and genomics approaches including RT measurements, replication
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; Cell, 2024; Nature, 2026). These discoveries have further led to the unexpected finding that RNA-binding proteins (RBPs) are common components of the cell surface (Cell, 2025; Nature Biotechnology, 2025
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pharmaceutical engineering, materials chemistry, EV biology, immunology, protein and genetic engineering, and data science. The current focuses of our group include biohybrid lipid nanoparticle platform
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; design and optimize synthetic strategies for complex peptides, peptide libraries, and small proteins; develop scalable production methods using solid-phase peptide synthesis and native chemical ligation
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Max Planck Institute of Molecular Physiology, Dortmund | Dortmund, Nordrhein Westfalen | Germany | about 1 month ago
and proven interest in mechanistic cell biology Experience in any of the in relevant areas: genetic engineering in eukaryotic cell lines, protein purification (recombinant and native), advanced optical
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molecular biology techniques, such as design of plasmids/proteins to fulfill desired purposes, methods for detecting proteins of interest (by e.g., flow cytometry, fluorescence microscopy or binding assays
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numerical simulations to understand molecular mechanisms of epigenetic regulation by the Polycomb and Trithorax group proteins. Project description Chromosomal rearrangements of the human MLL1 gene
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disordered regions (IDR) in G protein coupled receptor signaling. The candidate will leverage protein engineering and biosensor techniques established in the lab and collaborate with researchers in the lab
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for theranostic applications. Develops and optimizes bioconjugation strategies for peptides, antibodies, proteins, and small molecules. Performs analytical characterization using techniques such as HPLC, LC-MS, NMR
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The laboratory investigates organelle biogenesis and maintenance, with a focus on the cell biology membrane lipids. Our goal is to elucidate an integrated understanding (lipids and proteins