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that are produced to help them adapt to the challenges of surviving in diverse environments. The postdoctoral associate will be responsible for: protein production, purification, and analysis, including development
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mechanisms underlying protein–RNA interactions and their regulation. We combine structural, biophysical, cellular and computational approaches to understand how RNA-binding proteins recognise their partners
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analysis. - Knowledge of protein biochemistry and chromatographic techniques. - Knowledge of structural and molecular approaches for protein characterization. - Experience in the analysis of antibodies
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to understand dynamic molecular mechanisms underlying protein function. We integrate structural biology, electrophysiology, quantitative biophysics, and computational approaches to visualize transient molecular
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experience with mammalian cell culture, protein expression (E. coli, yeast, and mammalian cells) and purification, and/or Drosophila genetics, including dissection, immunostaining, and confocal microscopy
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | about 7 hours ago
coordinate across individual cells. The grant includes single-cell multi-omics sequencing, 4i protein imaging, CITE-seq validation, and AI-based cytogenetic analysis. Minimum Education and Experience
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modulations that occur within the oligomers constituted by mu-opioid receptors and other G protein-coupled receptors, such as dopamine and adenosine receptors. These complexes are responsible of opioid
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in fluorescence resonance energy transfer (FRET) assay to study protein-protein interactions. Skills for handling biochemical issues and experimental techniques. Good knowledge of the English language
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), assessing protein quality for subsequent characterization and structural analysis; performing biochemical and biophysical assays to assess sample stability, folding and oligomerization state, as
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Contract type: Fixed-Term (1 year) / Full-time MRC Protein Phosphorylation and Ubiquitylation Unit (MRC PPU) The MRC PPU is one of the world's leading centres for research on protein phosphorylation