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regulate peripheral organs. In this program, we combine molecular profiling, neural activity measurements, circuit perturbation, anatomical mapping, and metabolic phenotyping to identify the pathways through
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project based on their interests while building on ongoing work in the lab. The successful candidate will gain expertise in CRISPR screening, drug sensitivity profiling, target deconvolution, and the
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candidate will gain expertise in CRISPR screening, drug sensitivity profiling, target deconvolution, and the computational analysis of large-scale pharmacogenomic datasets. The lab maintains active
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• Primary cell culture and tissue based analyses • Transcriptional profiling, including bulk and single cell RNA sequencing • Metabolomics and lipidomics relevant to retinoid biology • Quantitative retinoid
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169, 350–360 (2017). PMC5616215. Polacco BJ, Lobingier BT, Blythe EE, Abreu N, Xu J, Li Q, Naing ZZC, Shoichet BK, Levitz J, Krogan NJ, von Zastrow M, Hüttenhain R. Profiling the diversity of agonist
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for all postdoctoral scholars appointed through the Office of Postdoctoral Affairs. The FY27 minimum is $79, 056. Our lab recently developed a new methylation profiling technology, FLEXseq (PMID: 42130071
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tissue voxels into indexed multi-well plates, enabling spatially indexed sampling that remains compatible with conventional high-depth molecular assays such as RNA sequencing and epigenomic profiling
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and/or related fields including genetic epidemiology, human genetics, biostatistics, bioinformatics, computational biology, or phenomics (including EHR, deep medical imaging, and biomarker profiling