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extracellular polymers, bacteria growing in biofilms survive antibiotic concentrations orders of magnitude above those that eradicate the same strain in suspension. The matrix limits penetration, internal
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strategies. This position offers a unique opportunity to work at the interface of discovery and clinical translation, leveraging circulating tumor cells (CTCs), extracellular vesicles (EVs), circulating tumor
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misfolding, extracellular vesicles and propagation of disease in neurodegeneration. We use iPSC from patients with Alzheimer’s Disease and other types of neurodegenerative diseases as our model system, in
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include animal experiments, maintain mammalian cell cultures, transfections, transductions, isolation and characterization of extracellular vesicles, and isolation and analysis of nucleic acids, etc
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | about 2 months ago
service. Position Summary We are looking for a highly motivated postdoctoral associate/s with a strong background in extracellular vesicles, nanoparticle preparation, and protein production. The successful
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, chemistry and physics to study lipid-based nanoparticles. We characterise the composition and distribution of molecules in synthetic and naturally occurring nanoparticles (including extracellular vesicles
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dissects the cellular and molecular pathways that shape immune responses to alloantigens and EBV, with an expanding emphasis on how extracellular vesicles mediate intercellular communication and modulate
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. The project will also intersect with analysis of extracellular vesicle and with other therapeutically relevant agents. Findings will be validated in human tissue samples to ensure biological relevance. By
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including RNA, DNA, and extracellular vesicles isolations, QPCR, western blot, microarrays, and RNA sequencing is expected. Experience with flow cytometry is preferred. Experience in the analysis of genomics