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RAP opportunity at National Institute of Standards and Technology NIST Design, Development and Evaluation of Surface Plasmon Resonance Imaging as a Quantitative Microscopy of Live Cells and
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plasmon resonance methods to assess the antigen binding kinetic measurements of antibodies induced by vaccination in human clinical and pre-clinical vaccine trials for HIV, malaria, tuberculosis and other
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high throughput surface plasmon resonance (SPR) and bio-layer interferometry (BLI) assays to identify lead monoclonal antibody and other biologics candidates for therapeutics development. Perform complex
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(cloning, expression, purification), crystallography (crystallization, optimization, data collection and structure determination), biochemistry (enzyme kinetics) and biophysics (Surface Plasmon Resonance
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systems, exploring phenomena such as exciton-polaritons, plasmonics, and non-linear optics. Organize collaborations with industry partners or government agencies to translate research findings
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dynamics, and other phenotypic characteristics, in single cells. Imaging modes that employ fluorescence, transmitted light, quantitative phase, and/or surface plasmon resonance microscopy may be used
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simulation, complementary biophysical techniques such as surface plasmon resonance, and advanced data analysis techniques, neutron reflectivity has proven to have unique advantages for studying the structural
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of the system. This model can be extended to include electromagnetic effects such as plasmon-phonon coupling that may be important for electronic nanomaterials. We propose to apply the CGF technique
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on incorporating novel, high-throughput forms of single particle EV detection schemes involving nano-flow cytometry, microfluidics, plasmonic or fluorescence imaging using nanoparticles, droplet digital PCR and/or