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Field
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., Alzheimer’s or Parkinson’s) and a track record of first author publications, a plus. Experience with the development and validation of advanced cellular models, such as induced pluripotent stem cell–derived
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that has pooled its expertise to tackle fundamental questions in neuroscience – questions such as, "How do neural stem cells choose between self-renewal and differentiation?" "What mechanisms generate
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the following key topics: Molecular mechanisms governing the lineage plasticity of lung stem cells. Intercellular crosstalk between lung stem cells and their niche. Inflammatory memory of lung stem cells during
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responses to cancer therapies in human induced pluripotent stem cells) data for elucidating molecular mechanisms for health outcomes; and 3) evaluating health disparities through pharmacogenomics
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hematopoiesis. 2) Delineating the role of long noncoding RNAs in regulating CTCF boundary function during hematopoiesis and leukemogenesis. 3) Epigenetic and transcriptional regulation of hematopoietic stem cell
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-molecular condensation in live cells. We are using mouse embryonic stem cells and mouse erythroid leukemia cells to investigate the dynamics and function of transcriptional condensates in health and disease
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mechanisms. Al-based analyses will identify key molecular pathways for mechanistic investigation in primary human trophoblasts, trophoblast stem cells, placental organoids, and related experimental systems