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preclinical pharmacology to lead the biological validation arm of the laboratory’s target discovery program. The laboratory applies chemoproteomic and chemical biology approaches to identify the protein targets
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the mechanisms of canonical Wnt pathway have been extensively studied, it is yet not understood how nuclear protein β-catenin can drive the wide arrays of transcriptional responses depending on the context
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Wnt pathway have been extensively studied, it is yet not understood how nuclear protein β-catenin can drive the wide arrays of transcriptional responses depending on the context or developmental stage
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was traditionally considered to be confined to the nucleus and cytoplasm, recent studies have revealed that a subset of RNAs is glycosylated and displayed on the cell surface (cell surface glycoRNAs) (Cell, 2021
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research Medical sciences » Other Researcher Profile First Stage Researcher (R1) Positions PhD Positions Application Deadline 31 Jul 2026 - 23:59 (Europe/Warsaw) Country Poland Type of Contract Temporary Job
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of actin-based motility in the intracellular bacterial pathogens Shigella and Listeria. These pathogens use the surface proteins IcsA and ActA to recruit host actin-regulatory factors and generate actin
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screening studies enabled the selection of four novel 1,3,4-thiadiazole derivatives that display anticancer activity against GBM cells and are relatively less toxic towards human astrocytes. Particular GBM
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follow @NaturePortfolio. About The Role Nature Reviews Molecular Cell Biology (https://www.nature.com/nrm/ ) is a world-leading journal that publishes authoritative and accessible Reviews, Comments and
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using displayed targeting ligands, combining capsid engineering, functional screening, and mechanistic analysis. It is expected that the postdoc will work with an established AAV production platform and
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characterizing microbubbles, including shell composition design, PEGylation chemistry, and protein or lipid bioconjugation. Experience with acoustic characterization of microbubbles, including in vitro ultrasound