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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | about 1 month ago
. Structural Biology: We use cryo-electron microscopy to reveal the molecular interactions between a drug and its receptor. This provides useful information for probing specific atomistic mechanisms that drive
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particular, the main focus of the research will be on the operando Electrochemical Liquid Phase Transmission Electron Microscopy (EC-LPTEM), that will be complemented with one or more of the spectroscopic
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to treat cancer and inflammatory diseases. The work will require mastering a broad spectrum of skills from fluorescence microscopy, nanomedicines, biomaterials, immunology, and cancer biology. In addition
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-tube synthesis, mechanical alloying, spark plasma sintering); • Crystal structure determination and microstructural characterization (X-ray diffraction, electron microscopy, spectroscopy
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practical expertise in at least one of the project’s core areas: structural biology, particularly X-ray crystallography or cryo-electron microscopy; protein biochemistry, including protein purification and
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systems. Main tasks include material synthesis and characterization, low-temperature scanning tunnelling microscopy and spectroscopy, data analysis, scientific instrumentation, collaborative research
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electron microscopy. Documented experience in photophysical characterization, including UV–Vis absorption spectroscopy, steady-state and time-resolved photoluminescence spectroscopy, PL quantum yield
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-on experience with recombinant protein production and purification and preferably with actin biochemistry, fluorescence microscopy, cryo-electron microscopy or cryo-electron tomography. Experience in cryo-EM
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interactions. The facilities include full-service histology, microscopy (fluorescent, confocal, and electron), tissue culture, animal surgery and imaging rooms, providing a rich scientific environment for basic
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and aspects related to safety and best practices. The candidate will make extensive use of state-of-the-art imaging, spectroscopy (Raman, electron microscopy, infrared, etc.) and scattering methods