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knowledge of phylogenetic and statistical methods used in analysis of molecular data; documented proficiency in bioinformatics tools for the analysis of data generated using next-generation sequencing (NGS
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, in the transition between the two catalytic conformations of the spliceosome. Our current model predicts that direct interaction between the Prp8-RT beta-hairpin loop and the U2 sequence between helix
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Description of programme/project/undertaking Recent developments in biotechnology, including the enormous progress in sequencing technologies and public accessibility to many bioinformatic data, create new
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Recruitment for the position of Assistant Professor in the Laboratory of Genomics and bioinformatics
Hirszfeld Institute of Immunology and Experimental Therapy Polish Academy of Sciences | Poland | about 1 month agoidentification of genetic variants and integration of molecular, biological and clinical data. 3. Consulting on research projects concerning experimental design, selection of sequencing methods, and assessment
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-throughput data, particularly next-generation sequencing data. Experience in the analysis of Hi-C and HiChIP data. Very good knowledge of at least one programming language used in data analysis, such as Python
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in multiple compartments of the cell. In this project, we will establish a global solution to predict the organellar localization of unknown proteins. To this end, we will conduct a comprehensive
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/destabilization of several postulated intermediate structures of the catalytic triplex on splicing catalysis. The RNA core of the spliceosome undergoes multiple changes during the catalytic phase of splicing
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include: Cell culture. Generation of functional mutants using conventional transfection methods and/or CRISPR–Cas9 genome editing. Preparation of sequencing libraries, including HiChIP, ChIP-seq, and CUT
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-generation sequencing (NGS) libraries and in the bioinformatic analysis of sequencing data. RESPONSIBILITIES: The successful candidate will perform their duties in accordance with the strategic objectives
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of the Faculty of Medicine • Develops curricula • Prepares research papers aligned with the Clinic’s profile Work Location(s) Number of offers available2Company/Institute Department of General and Transplantation