-
decoded by downstream regions. In the lab, we interleave multi-compartmental modeling (NEURON simulation platform), electrophysiology (extracellular single-cell recording and intracellular patch-clamp), and
-
cryo-electron microscopy to determine protein structures, employ biochemical and biophysical methods to characterize protein functions, and use molecular dynamics simulations to understand the structural
-
genome-wide copy number and gene expression, histology, and mutations. Together, these tools and approaches will lead to a better understanding of kinase signaling in thyroid cancer, reveal how different
-
decoded by downstream regions. In the lab, we interleave multi-compartmental modeling (NEURON simulation platform), electrophysiology (extracellular single-cell recording and intracellular patch-clamp), and