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program focused on understanding how RNA modifications regulate gene expression and cellular function in health and disease. Our laboratory investigates the molecular and biological functions of m6A
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therapeutic resistance in lung and head and neck cancers using integrated genetic, molecular, and computational approaches. We are particularly interested in discovering new therapeutic vulnerabilities and
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include flow cytometry, tissue histology, molecular and cellular assays, analysis of muscle degeneration and regeneration, and integration of single-cell/genomic data to define therapeutic mechanisms. Min
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earth elements, cobalt, lithium and other metals. The research aims to: 1) Delineate the molecular level speciation and mineral phase associations of these critical metals in unconventional feedstocks; 2
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, and large-scale simulation. The successful candidate will contribute to the development of an HIV epidemic simulation that integrates dynamic social and sexual networks, heterogeneous susceptibility and
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laboratory within the Department of Medicine and Duke Cancer Institute Center for Prostate and Urologic Cancers is a multi-investigator translational research laboratory focused on molecular mechanisms
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Lab’s recent studies on gene regulation, stem cell biology, genome organization, and tissue regeneration have been published in leading journals, including Molecular Cell 2022, Nature Genetics 2023
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, molecular biology, pharmacology, and/or a related field. Experience with cell culture, mouse models, and biochemistry/molecular biology is required. Familiarity with gene sequencing techniques/data analysis
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related field, with strong experience in molecular and cellular biology, molecular biology–related bioinformatics, flow cytometry, and cell culture. The candidate should be highly motivated, organized, and
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the tumorigenicity of WT, D16, and p95 HER2 and using these models to test whether HER2 ICD- and p95 HER2-based vaccines generated by the laboratory prevent isoform-driven tumor formation Histological and molecular