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research group investigating synaptic function and calcium channel signaling in health and disease. Our research combines neuronal cell culture models, molecular and biochemical approaches, fluorescence
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and the African turquoise killifish to model human cardiovascular diseases, polycystic kidney disease (PKD), and cardiac aging. Our research aims to uncover the molecular and cellular mechanisms
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simulations, enhanced sampling, and kinetic modeling. Research activities will examine molecular interactions involving neurotransmitters and hormones, including norepinephrine and estrogen, and their effects
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observables in both systems. Anderson, P.W. 1972. More is di1erent. Science 177:393-396. Eberl, G. 2026. An elementary model of homeostasis and immunity that generates symbiosis. bioRxiv https://doi.org
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on the specific questions addressed, approaches may include mammalian cell culture, molecular and cell biology, genetic perturbation, imaging, epigenetic and chromatin profiling, and in vivo models of early
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sample, and in vivo leukemia models Perform and oversee molecular, cellular, genomic, and functional assays Analyze, interpret, and integrate multi-omics datasets to generate biologically meaningful
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secondments (lab exchanges). The doctoral candidate will utilize cutting-edge techniques: Cell and tissue culture (human primary and stem cell-derived retinal models) Molecular biology and biochemistry
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cells. Compounds identified through a pharmacological screening approach represent promising therapeutic leads, including in models of bortezomib-resistant cell lines. The project combines a fundamental
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interpretable models that connect molecular patterns across multiple scales of human biology. The project lies at the interface of artificial intelligence, computational biology, systems medicine, and precision
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production provides a competitive advantage to commensal bacteria, thereby limiting the establishment of pathogenic strains. This work adopts a multidisciplinary approach, combining methods from molecular