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the Laboratory, the role will undertake high-quality experimental research using a range of molecular, cellular and animal model techniques to advance the understanding and treatment of cancer. Working
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metabolism. We previously discovered new mito-SEPs (mitochondrial sORF-encoded peptides) (Zhang et al., 2020, Nature Communications) and are working on defining their molecular functions, with a special focus
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work from this program includes two key studies in Cancer Discovery that define the molecular and spatial progression of ovarian cancer precursors. One study used multimodal spatial profiling to reveal a
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opening of our state-of-the-art Molecular Sciences Building . We recently completed the strategic expansion of our academic staff, and we continue to invest in teaching and learning excellence . As part of
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(ESCs, iPSCs), directed differentiation, and advanced cell biology techniques; Be proficient in gene editing (CRISPR-based methods), molecular cloning, and functional assays; Demonstrate strong analytical
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metabolism. We previously discovered new mito-SEPs (mitochondrial sORF-encoded peptides) (Zhang et al., 2020, Nature Communications) and are working on defining their molecular functions, with a special focus
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alternative delivery systems, targeted delivery, cancer immunology, auto immune disease, primary human cancer cells, cancer and stem cell transplantation models, mouse genetics, molecular biology, biochemistry
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inheritance during development. You must be ambitious and able to work independently. Applicants should have, or will soon have, a PhD in genetics, biochemistry or molecular biology with a basic knowledge of
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-rich carriers of doxorubicin siRNA targeting oncogenes, as well as plasmids expressing tumor suppressor genes, to reduce breast cancer growth in a mouse model. These therapeutic agents will be evaluated
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Fellow position. The Arlotta lab at HSCRB is working to identify the cellular and molecular pathways disrupted in brain disorders such as schizophrenia and autism, by utilizing recent advances in genetics