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, rational drug design, and molecular modeling to improve potency, isoform selectivity, and drug-like properties. The project also involves the multistep synthesis, purification, and structural
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at https://biffilab.wordpress.com Pancreatic ductal adenocarcinoma (PDAC) remains a formidable clinical challenge. A major recent advance has been the development of KRAS inhibitors, which have shown
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the development of therapeutic strategies to promote neurological recovery. The successful candidate will use a combination of in vivo and in vitro approaches, including animal models, molecular and
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Kang | Department of Pathology ) and review our recent publications (https://www.ncbi.nlm.nih.gov/myncbi/zizhen.kang.1/bibliography/public/ ). Applicants should have a strong background in molecular
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Biostructural Group develops computational approaches for the analysis of chemical and pharmacological data, ligand–target relationships, structure–activity relationships, pharmacophore modeling, and molecular
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demonstration of a DNA-based stack data structure and recent advances in optimisation for DNA nanotechnology, the project will design, model, implement, and experimentally validate novel molecular data structures
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research group investigating synaptic function and calcium channel signaling in health and disease. Our research combines neuronal cell culture models, molecular and biochemical approaches, fluorescence
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and the African turquoise killifish to model human cardiovascular diseases, polycystic kidney disease (PKD), and cardiac aging. Our research aims to uncover the molecular and cellular mechanisms
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simulations, enhanced sampling, and kinetic modeling. Research activities will examine molecular interactions involving neurotransmitters and hormones, including norepinephrine and estrogen, and their effects
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observables in both systems. Anderson, P.W. 1972. More is di1erent. Science 177:393-396. Eberl, G. 2026. An elementary model of homeostasis and immunity that generates symbiosis. bioRxiv https://doi.org