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the same genetic material generate markedly different cells, and how this information is encoded within the genome. We utilize stem cells and cancer model systems, though projects range across disciplines
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established internationally recognized experimental platforms for the study of intraerythrocytic parasites, parasite metabolism, chemical biology, and preclinical models for therapeutic discovery and
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, including the PBWT/GBWT family of haplotype algorithms for biobank-scale identity-by-descent (IBD) detection, the Med-BERT and CovRNN clinical foundation models for electronic health records, and the UDIP
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research Strong quantitative skills, including experience with regression, structural equation modeling (SEM), and multilevel modeling (MLM) Experience with measurement development, factor analytic methods
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, bioengineering, or a related field - Strong background in molecular biology, cell biology, immunology, animal models, neuroscience, or translational research - Demonstrated ability to conduct independent research
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of research, scientific communication, and the translation of computational models into clinically meaningful tools. Individual development goals will be established at the beginning of the appointment and
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, and therapeutic engineering. Projects may involve immunotherapy models, CRISPR-based perturbation and screening, mRNA therapeutics and vaccines, protein engineering, systems immunology, and tumor
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. Building on this platform, we combine cell biology, biochemistry, CRISPR-based approaches, organelle isolation, metabolomics and proteomics, mouse genetics, and disease models to discover principles of ER
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AI can accelerate provenance research processes, including especially the use of Large Language Model based transcription of printed and handwritten documents, and subsequent extraction of knowledge
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Postdoctoral Associate | Mitochondrial Genomics | Lake Lab — Yale University, Department of Genetics
high-throughput screens, and building novel cellular models to reveal mechanisms of mitochondrial genome dysfunction. The lab is located in the Yale School of Medicine which offers an outstanding