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original research using the model system Caenorhabditis elegans together with mammalian cell systems to study how RNAs with expanded nucleotide repeats cause broad cellular energy metabolism disruptions
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-ray microtomography (XMT), Small-Angle X-ray Scattering (SAXS), Dynamic Vapour Sorption (DVS), and micropipette aspiration. The project will also involve advanced oral tribology using model interfaces
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tribology using model interfaces such as PDMS-saliva and porcine tongue, in-contact fluorescence imaging, and sensory evaluation in model and real food matrices. These complementary approaches will be
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these effects. The successful candidate will conduct original research using the model system Caenorhabditis elegans together with mammalian cell systems to study how RNAs with expanded nucleotide