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Join the Antigen Evolution & Design Lab as our first postdoctoral researcher and help define the future of AI-driven antigen evolution and vaccine design. We are seeking a highly motivated early
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addressed by harnessing advances in tissue engineering, via the design of new organ-on-chip models that mimic features and functions of human lymphoid tissues in vitro. In this project, we will take advantage
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models. Current treatment strategies for HBV are life-long and rarely curative. Finite antiviral and immunomodulatory therapeutic strategies are being pursued for an HBV functional cure to treat the 254
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of peptidoglycan, mass spectrometry, cellular and animal models, and in confocal/immunofluorescent microscopy. The postdoc will study the model organism Helicobacter pylori and its mechanisms of release of immune
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immunotherapy interventions targeting CD4+ T cells based on recombinant monoclonal antibodies or mRNA-containing lipid nanoparticles. The project will be primarily developed in a pre-clinical murine model of lung
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-learning model. Expected outputs include parameter priors, benchmarking results, a simulation pipeline, curated synthetic datasets, and Bayes optimal errors. Publication / conference: Depending on progress
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, the causative agent of leptospirosis, offers an excellent model for studying the mechanisms underlying host adaptation and zoonotic emergence. Virtually all mammalian species can act as reservoirs
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dynamics during regeneration, aging, and cancer, and how these processes can be modulated. Our research is primarily conducted in vivo. We combine genetic mouse models (lineage tracing, conditional
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models, flow cytometry, confocal microscopy and unbiased approaches such as single cells transcriptomics, spatial transcriptomics and epigenetics to characterize molecular and cellular mechanisms. Using
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Islands. NPJ Genomics Medicine. 2019 Jan 21;4:1. de Chaumont F. et al. Live Mouse Tracker : real-time behavior analysis of groups of mice. Nature Biomedical Engineering 2019 3(11):930-942. Huguet G. et al