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independent Postdoctoral Researcher in Bioorganic or Medicinal Chemistry with a focus on modulators of mitochondrial enzymes in neurodegeneration. The successful candidate will participate in research
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function contribute to chronic disease development. Our research investigates how mitochondrial dysfunction, immunometabolic reprogramming, cellular senescence and persistent inflammatory responses
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Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description Study of the role of mitochondrial calcium in the
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Position Summary The primary goal of this position is to investigate and characterize the molecular events that regulate calcium-induced, reactive oxygen species-sensitized, mitochondrial dysfunction
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Jastroch laboratory. The project addresses molecular mechanisms of mitochondrial bioenergetics, combining molecular simulations and systems levels-models with biochemical, physiological, and metabolic data
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Università degli Studi di Roma Tor Vergata - Dipartimento di Biologia | Roma, Lazio | Italy | 18 days ago
. Metabolic changes in all the cell types involved will also be investigated in depth, focusing on energy production and mitochondrial oxidative stress. Characterization will be carried out using omics
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inflammation, mitochondrial dysfunction, cellular senescence, chromatin regulation, and extracellular-matrix remodeling. The long-term objective is to establish a research foundation for visualizing
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interface, leading to progressive dysfunction and loss of choroidal endothelial cells, RPEs cells, and Photoreceptors in advanced disease. While Chr1 risk is known to impair RPE (e.g., mitochondrial
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; 2. Assessment of mitochondrial membrane potential, reactive oxygen species (ROS) production, and mitochondrial mass by flow cytometry; 3. Determination of mitochondrial DNA (mtDNA) copy number by RT
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. Understanding and experience with oxidative stress and mitochondrial function assays which include measuring reactive oxygen species and mitochondrial bioenergetics. f. Simulating microgravity