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primary goal of this position is to investigate the molecular mechanisms underlying calcium-induced, reactive oxygen species-sensitized mitochondrial dysfunction and its role in chronic disease and cellular
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tissues. Defects in mitochondrial translation, often caused by missing post-transcriptional modifications of mitochondrial tRNAs, are a major cause of severe diseases. Among these, the C5-taurinomethylation
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mitochondrial enzyme that plays a pivotal role in linking mitochondrial homeostasis to innate immune signalling. This PhD project proposes to explore NME4’s dual functions in nucleotide metabolism and
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Sciences, University of Copenhagen, investigates how mitochondrial dysfunction, cardiolipin metabolism, and endocrine stress signals drive skeletal muscle decline during aging. We combine mouse models of
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based on targeting the mitochondrial protein VDAC in tumours and neurodegenerative diseases. The first objective is to interfere with the VDAC-Hexokinase-1 (HK1) complex, which plays a central role
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, Department of Biomedical and Clinical Sciences, Division of Medical Chemistry and Cell Biology, Mitochondrial Genome Maintenance and Expression Group is recruiting a researcher for a temporary position
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date is negotiable. More about the position This position offers a unique opportunity to help uncover how DNA repair and mitochondrial transcription shape neuronal resilience in Parkinson’s disease
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scalable framework combining whole-genome sequencing (WGS) and direct long-read RNA sequencing (dRNA-seq) for high-resolution characterization of the human mitochondrial genome. A key innovation is MitSorter
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Summary: The Homa Majd Laboratory at Yale University School of Medicine seeks a highly motivated, ambitious, and curious Postdoctoral Associate. We study how metabolic and mitochondrial stress affects
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NIH Postdoctoral Position: Translational Research in Aging and Age-related diseases Postdoctoral fellows with a background in mitochondrial biology and oxidative stress are especially encouraged to