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Field
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preconception environmental exposures in animal models. Contribute to research projects investigating seminal plasma metabolomics, sperm mitochondrial biomarkers, and related mechanisms influencing reproductive
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functions and how these metabolic adaptations may be targeted therapeutically. Our research employs cell signaling and metabolism, fibroblast-immune cell crosstalk, metabolomics, mitochondrial biology
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, focusing on mitochondrial damage and airway hyperresponsiveness. Policy, led by the Texas A&M Transportation Institute, where we will assess how heat and air pollution mixtures may be modified by real-world
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oxidative stress and mitochondrial function assays which include measuring reactive oxygen species and mitochondrial bioenergetics. f. Simulating microgravity conditions to study physiological responses. g
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neurodevelopmental, neuropsychiatric, or neurodegenerative disorders, with particular emphasis on the role of mitochondrial dysfunction and metabolic deficits in disease progression. To address these questions, we use
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microvascular dysfunction in diabetes and menopause, particularly in cell-cell communication, mitochondrial function, cell apoptosis/senescence, and calcium handling in the endoplasmic reticulum of endothelial
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real-time PCR is required. Previous experience/knowledge in animal experiments is much preferred, and experience in cardiology and mitochondrial physiology research is a plus. In addition, capabilities
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understand 1) the development of insulin resistance and increased liver glucose production, that contributes to hyperglycemia in patients with obesity and type 2 diabetes; 2) the impairment of mitochondrial
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membrane, synaptosomes, and other compartments relevant to mechanistic studies. Integrate multi‑modal datasets to investigate molecular pathways including neuroinflammatory cascades, mitochondrial