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mitochondria to sustain growth of clear cell renal cell carcinoma (Zhao et al. JCI Insight, 2025): https://insight.jci.org/articles/view/182711 What You’ll Do Lead 1-2 independent project. Design and execute
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of behavior (doi: 10.3389/fncel.2021.639322), electrophysiology (doi: 10.1111/jnc.14816), energy charge (by HPLC), redox status (colorimetry), mitochondria function (Sea Horse) and mitochondria biogenesis
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transport and transport-related maturation events. The TIM23 protein translocase plays a key role in establishing the proteome of mitochondria by two modes of action, protein translocation across and
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modifications to establish a novel ageing model using the ICE mouse. * Exploring various perspectives on the rate and timing of ageing, including stem cells, DNA damage, epigenome, mitochondria, and lipid
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to damage, with a primary focus on the endolysosomal system and mitochondria? What are the protein interaction networks that make up dynamic organelles? How to familial mutations in key organellar systems
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eukaryotic cell is its internal segmentation into sub-cellular structures called organelles, such as the nucleus, mitochondria, or endoplasmic reticulum. The segmentation allows for spatial separation and
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research, as well as animal studies to investigate the role of mitochondria in cancer and drug resistance. The incumbent is responsible for performing experiments under Dr. Glytsou’s direct supervision as
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, pharmacology or related fields. Certifications/Licenses Required Knowledge, Skills, and Abilities Preferred Qualifications Experience in mitochondria and/or neuroscience and/or aging and/or protein biology (or
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stressors. Emphasis on redox biology and/or mitochondria would be complementary to the strengths of the department which include neurodegenerative, pulmonary, and cardiorenal diseases, as well as maternal and
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of lentivirus/adenovirus/adeno-associated virus, cell transduction, cell line generation, live cell imaging, histology, microscopy, biochemical assays in cells, isolated mitochondria and tissue homogenates, PCR