The Petsalaki Group uses data-driven and network-based approaches to understand the principles underpinning context-specific cell signalling. We are an interdisciplinary team using computational and experimental approaches and methods from machine learning and network modelling to CRISPR and phosphoproteomics.
For this project you will be joining a multi-partner exciting collaboration funded by Open Targets to identify combination targets for KRAS-mutant colorectal cancer and triple negative breast cancer. This partnership includes the Garnett Group and industry partners from GSK and Sanofi.
You will be working in collaboration with the team to analyse the largest genetic interaction dataset generated to date in human cell lines (75K pairs across 50 cell lines) in order to prioritise candidate target pairs for therapeutic applications, understand the mechanisms and principles underpinning these genetic interactions. Additionally you will have the opportunity to develop a predictive model of drug synergy that is also interpretable in terms of mechanism of action.
Postdoctoral Researcher Position In The Laboratory Of Cell Biology, International Institute of Molecular and Cell Biology in Warsaw, Poland, about 9 hours ago
Laboratory of Cell Biology https://bit.ly/3ptdp4V at the International Institute of Molecular and Cell Biology in Warsaw (IIMCB), headed by Professor Marta Miączyńska is looking for a Postdoctora...
Junior Fellow In Cancer Immunology – Lugli Lab, Humanitas Research Hospital, Italy, 18 days ago
The Laboratory of Translational Immunology is currently seeking a highly motivated junior scientist at the postbac (post “laurea”) level to study the cellular and molecular mechanisms of memory T ...
Research Fellow Biological Sciences, Times Higher Education, United Kingdom, 24 days ago
Job Description The laboratory of Assistant Professor LIN Zhewang at the Department of Biological Sciences, National University of Singapore (NUS) is seeking a creative and highly motivated postdo...
Postdoc (M/W/D), E13/100 % , Technical University of Munich, Germany, about 3 hours ago
31.05.2021, Wissenschaftliches Personal We are looking for a scientist (Postdoc, m/w/d) who shares our enthusiasm about human T cell engineering and to work on our new project entitled “CRISPR-dis...
Research Assistant, Pharmacy, Times Higher Education, United Kingdom, 23 days ago
Job Description The successful candidate will work with Dr Gloryn Chia on establishing empirical platforms for identifying and validating cancer vaccine candidates under a project on Cancer vaccin...
Postdoc, Nencki Institute of Experimental Biology, Poland, 14 days ago
Responsibilities: A postdoc position in the Laboratory of Molecular Neurobiology to study immune cells in murine genetically engineered models of brain tumors and immunotherapy using single cell a...