Staff Research Associate II (50% Limited)

Updated: 3 months ago
Location: Los Angeles, CALIFORNIA


  • JOB DUTIES

Description

The Department of Molecular and Medical Pharmacology is seeking a Staff Research Associate II to join our team. Under the guidance of a faculty supervisor, the selected candidate will be responsible for synthesizing organic intermediates and radiolabeled compounds for research purposes. The role involves the preparation of radiopharmaceuticals labeled with short-lived radionuclides, utilizing advanced radiopharmaceutical techniques Applying principles from organic and analytical chemistry, you will contribute to synthesis processes, ensuring the safe handling of gamma ray emitting radionuclides. Additionally, responsibilities include the application of rapid chemical and physical preparative and separation procedures, as well as assistance in developing fully automated systems for radiopharmaceutical preparations. You will also prepare and purify organic intermediates, with a focus on elucidating their structure through spectroscopic methods. Daily laboratory maintenance and support in regulatory and technical writing tasks are also integral aspects of this role. Note this is a 50% limited role which may convert to career. Hourly range: $28.04-$45.11



  • JOB QUALIFICATIONS

Qualifications

Required: * Knowledge of organic/analytical chemistry and radiochemistry; * Trained as an authorized user for radioactive materials; * Demonstrate ability with organic synthetic laboratory procedures; Ability to use all basic laboratory equipment, including centrifuge, pH meter, etc; Skill in chromatographic separations using open-column chromatography, thin-layer chromatography, high pressure liquid chromatography and gas-liquid chromatography; * Skill in safe handling of radioactive material; * Ability to follow nuclear safety rules, regulations, and procedures to ensure professional and safe working practices are followed at all times; * Understands the regulatory environment in terms of radiation safety and current good manufacturing practices; * Experience with regulatory and technical writing; * Ability to organize raw data into a comprehensible form; * Demonstrate ability to create and maintain up-to-date and accurate records; * Skill in following specific directions on detailed experimental protocols; Ability to communicate effectively to convey experimental results; Interpersonal skills to effectively interact with faculty, staff, postdoctoral fellows and students; * Demonstrated computer skills including knowledge of Excel, MS Word and WordPerfect and ability to adapt their use to the automation of radiopharmaceutical synthesis systems and data acquisition; * Ability to maintain laboratory readiness for future experiments; * Ability to communicate effectively to convey experimental results; * Demonstrated ability to maintain an organized workplace; * Knowledgeable in current GMP/GLP and regulatory requirements. Preferred: * Experience with in vivo imaging and animal rodents handling is a plus; * Experience with 68Ga, 177Lu, 99mTc, 225Ac is strongly desired. 18F experience is a plus; * Experience in radiopharmaceutical production, QC and laboratory operations; * B.Sc. in Organic Chemistry, Biochemistry, Biomedical Sciences, or a related discipline; Ability to perform radiolabeling/characterize products, 3+ years of experience in radiopharmaceutical manufacturing or related field.



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