Staff Research Associate 4 - 129860

Expert theoretical and demonstrated knowledge of biochemistry, molecular biology and genetics, including relevant laboratory techniques, acquired through a B.S. in Biology or related field OR an equivalent combination of education and laboratory experience. Graduate degree is preferred.

Extensive demonstrated experience, skill and knowledge in successfully carrying out independent research in molecular biology and cell biology, acquired through a combination of extensive study and experience.

Extensive knowledge of in vivo methods and tissue analyses.

Demonstrated experience in working with rodent models and surgeries including IP and AAV injections.

Demonstrated ability to independently perform functional assays to probe protein quality and function using established methods.

Demonstrated experience with mice as research model systems.

Strong knowledge of high-resolution confocal imaging of peripheral and central neural tissues, dissections, staining, and analyzing imaging data.

Demonstrated detailed conceptual/theoretical research experience, including independent experimental ability to successfully perform research techniques including but not limited to RNA, Western blotting, genotyping assays, PCR, RT-PCR, molecular cloning, genetic crosses,live imaging, protein purification, enzymology, various recombinant DNA techniques, protein gels, and confocal microscopy.

Extensive demonstrated experience with general laboratory equipment including spectrophotometers, centrifuges, balances, autoclaves, and pH meters.

Demonstrated ability to independently develop, follow, and troubleshoot established lab protocols and lab procedures.

Demonstrated ability to provide work direction to student workers. Skill to train others in basic lab support techniques and procedures (preparing media and solutions, dishwashing, equipment usage, etc.).

Excellent interpersonal, oral, and written communication skills. Demonstrated ability in using tact, diplomacy, discretion, and flexibility with diverse personalities and situations. Demonstrated ability to work as part of a research team and interact effectively with collaborating labs and others in scientific community.

Excellent organizational and administrative skills. Demonstrated skill to set up and maintain computerized and hard copy record keeping systems, and keep clear and accurate records.

Skill and knowledge to proactively maintain an organized lab and stocks of essential supplies and media, purchase new equipment, and ensure lab equipment is operating effectively.

Strong knowledge of purchasing and reimbursement procedures. Demonstrated ability to maintain purchasing records and monitor lab expenditures.

Experience in working with computers (Mac and PC) and software using graphics, word processing, spreadsheet, and internet programs with a willingness and ability to update and increase skills and knowledge as needed.

Experience and knowledge of proper handling, storage, and disposal of chemicals, biochemicals, hazardous chemicals, and biohazardous materials including radioactive materials.

Demonstrated ability to record scientific data in a well-organized laboratory notebook. Demonstrated organizational skills to keep clear and accurate records.

Strong knowledge of Cal-OSHA and UCSD EH&S safety requirements including MSDSs, hazard communication, laboratory safety precautions (i.e., appropriate clothing and shoes, use of protective items such as gloves and goggles as well as basic first aid procedures). Experience and knowledge of proper handling, storage and disposal of chemicals, biochemicals, hazardous chemicals and biohazardous materials. Ability to train personnel in correct safetyprecautions. Willingness and ability to keep safety training current and consistent with research involvement.

Willingness and demonstrated ability to embrace and consistently uphold the principles of community for a collaborative work environment

Experience in data analysis and developing non-standard data analysis pipelines such as AI-assisted segmentation of datasets.

Expertise in bioinformatics and neuronal biology

Demonstrated ability to manage a scientific project autonomously from beginning to end, with the ability to act independently and exercise sound judgment and prioritize and excellent organizational skills necessary to keep accurate records of experimental procedures.

Demonstrated ability to develop, follow and trouble-shoot established lab protocols and lab procedures with limited direction from PI.

Excellent skill and ability to conduct scientific literature searches using libraries and specialized research tools and databases on the internet.

Sensitivity to the needs and humane treatment of caged laboratory animals in compliance with AAALAC standards. Demonstrated experience in mouse colony handling, care, breeding, and management. Demonstrated ability to follow guidelines for care of laboratory animals.