Sr. Bioinformatics Analyst

Updated: 2 months ago
Location: Miami, FLORIDA

The University of Miami is considered among the top tier institutions of higher education in the U.S. for its academic excellence, superior medical care, and cutting-edge research. At the U, we are committed to attracting a talented workforce to support our common purpose of transforming lives through teaching, research, and service. Through our values of Diversity, Integrity, Responsibility, Excellence, Compassion, Creativity and Teamwork (DIRECCT) we strive to create an environment where everyone contributes in making UM a great place to work. We are one of the largest private employers in Miami-Dade County; home to more than 13,400 faculty and staff from all over the world.

This position reports to Dr. Xi Chen, Associate Professor of the Department. of Public Sciences and Director of the Biostatistics & Bioinformatics Shared Resource of the Sylvester Comprehensive Cancer Center. This position will work with research teams on facilitating the understanding of genetic and genomic variations in human diseases especially cancers with Bioinformatics analysis such as next generation sequencing (NGS) data analysis.  Individual will be responsible for developing, maintaining and implementing NGS analysis pipelines that perform QC, base calling, sequence assembly, verification and downstream annotations. Development and implementation of novel bioinformatics methods. Supervision and training of junior team members and data analysts.  Work on large-scale multi-disciplinary research projects in collaboration with Statisticians, biologists and clinicians.

Duties & Responsibilities:

Pipeline development:  Developing, maintaining, and implementing next generation sequencing data analysis pipelines that perform QC, base calling, sequence assembly, short-read alignment, genotype calling, transcript abundance, sequence annotation, and related bioinformatics methods. Developing and implementing novel NGS methods to improve the existing pipeline. This includes testing third-party software or development of novel methodology to fill gaps in the pipeline, as needed. Testing, characterization and integration of diverse third-party Bioinformatics algorithms;  applying state-of-the-art statistical, visualization and data mining methods;  working closely with lab-based experimentalists, clinicians and PIs to solve their Bioinformatics challenges. Analysis: Work with the Informatics group to provide support for large scale research projects, Sequencing Cores and the Center for Genomic Technologies; provide support for translational research in Clinical Genomics. Provide analysis of NGS data for genes and pathways, analysis of methylation data in epigenomics projects, micro-RNA target prediction; and developing and implementing new bioinformatics packages. Administrative: Supervision of junior bioinformatics team members and data analysts (e.g., statistical data analysts, post-docs, etc) on bioinformatics projects, as needed. Establishing standard operating procedures, documentation and scripts to generate custom reports. Developing materials for Bioinformatics tutorials, and training courses. Perform other duties as assigned.

The minimum requirements are: Bachelor’s Degree in Bioinformatics/Computational Biology/Computer Science or related field and three (3) years of experience working in Bioinformatics or a related field is required.  Master’s Degree/PhD in Bioinformatics/Computational Biology/Computer Science or related field is preferred. Any appropriate combination of relevant education, experience and/or certifications may be considered.

UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for. The University of Miami offers competitive salaries and a comprehensive benefits package including medical and dental benefits, tuition remission, vacation, paid holidays and much more. The University of Miami is an Equal Opportunity/Affirmative Action-Veteran/Disability Employer. Come join us!



Patient safety is a top priority. As a result, during the Influenza ("the flu") season (September through April), the University of Miami School of Medicine requires all employees who provide ongoing services to patients, work in a location (all Hospitals and clinics) where patient care is provided, or work in patient care or clinical care areas, to have an annual influenza vaccination. Failure to meet this requirement will result in rescinding or termination of employment.


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