Updated: 21 days ago
Location: Durham, NORTH CAROLINA
Deadline: The position may have been removed or expired!

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

Grant/sponsor funded [50% or more external]

RESEARCH ASSISTANT position in the Lefkowitz lab at Duke University, Department of Medicine

The Lefkowitz laboratory in the departments of medicine, biochemistry, and chemistry is looking for a driven and motivated Research Assistant.

The lab seeks to understand the molecular mechanisms of a family of cell-surface proteins called G protein-coupled receptors (GPCRs) by applying methods in biochemistry, structural biology, medicinal-chemistry, and signaling. GPCRs are the targets of roughly one-third of all prescribed human therapeutics. They impact all aspects of physiology and human disorders, including cardiovascular, neurological, cancer, and metabolic. This position will be working with a highly experienced assistant professor to develop chemical modulators of GPCR singling proteins and dissect molecular mechanisms using pharmacological, medicinal chemistry, and structural biology approaches including electron microscopy imaging. The ideal candidate will assist in experimental data analysis and interpretation while demonstrating excellent communication skills

The ideal candidate will be not only innately curious but also someone who has a passion for continuing to push the boundaries of our understanding. The ideal candidate would be interested in joining the lab immediately with a minimum 1-year commitment. The position is perfect for post-bac gap-year students, particularly those who want to pursue MD, Ph.D., or MD/Ph.D. studies and, thus, are highly encouraged to apply.

Candidates with BS/MS degree whose majors in biology, biomedical engineering, neuroscience, or chemistry are preferred; all motivated students from other natural science majors will be considered.

If interested in this exciting opportunity, send a paragraph describing your interest and CV via email attachment to: Dr. Alem Kahsai ( and Dr. Robert Lefkowitz ( ).

Minimum Qualifications

Work generally requires skills acquired through the completion of a bachelor's degree in botany, biology, zoology, psychology or other science related scientific field program.


Work requires two years of research experience. A related master's OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE degree may offset required years of experience on a 1:1 basis, e.g., a two year master's degree in lieu of two years of experience.

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

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