RESEARCH TECHNICIAN I

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

Occupational Summary

The Macias Lab is seeking a highly motivated and team-oriented research technician. We are a translational cancer research group with a focus on validating novel therapeutic drug targets and conducting studies to define mechanisms of action.

Work Performed

Duties will include wet lab work, general lab management, preclinical rodent studies and rodent husbandry. The research technician will perform a variety of cell culture in vitro studies with cancer cell lines and patient derived tissues. With training, mastery of routine cell culture maintenance, cell proliferation assays and molecular biology techniques such as protein western blot, gene expression qPCR are expected.  General lab management duties will include ordering and stocking of lab supplies, maintaining laboratory equipment, inventory of cell lines/specimens/animals/inventory and perform other related duties and special projects as requested. Rodent work will include maintenance of mouse colonies (breeding and genotyping), assistance with genetically modified cancer cell line tumor growth and drug efficacy studies.  The technician is expected to help with tumor cell inoculation (subcutaneous and orthotropic via survival surgeries), dosing, tumor measurement (caliper or in vivo imaging) and general monitoring of animal wellbeing.

Minimum Qualifications:

Must be well organized with an attention to detail. Experience handling rodents is necessary, aptitude for learning to carryout survival surgeries and conducting experiments with tumor cell lines in vivo is highly desired for application. Experience with molecular biology and in vitro cell culture techniques are preferred but not required for application with the expectation that the research technician be willing to get trained in these techniques.

Education:

Requires a bachelor’s degree in biology, animal sciences or other science related field.

Experience

None required above education/training requirement OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE

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