RESEARCH SCIENTIST/ENGINEER 4

As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem solving skills and dedication to build stronger minds and a healthier world.

UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty. 

Department of Medicine: Allergy and Infectious Diseases has an outstanding opportunity for a Research Scientist/Engineer 4.

Field of Research:
Perform and guide research pertaining to structure-based drug design. Assay bacterial, viral, and parasite proteins for x-ray crystallography, and biochemical assays. Member of the Seattle Structural Genomics Center for Infectious Disease, SSGCID.

Purpose of Research:
Lead a team of researchers working on scientific community nominated targets in a pipeline to clone, express, purify protein and help determine/ produce a X-ray crystal structure for use in new drug development.

RESPONSIBILITIES:

• Designing SOPs, establishing routine weekly lab duties, and assigning these duties to other lab members.  Establish weekly production goals for cloning, expression-testing, upscales and purifications.  Keep track of weekly production achievements and failures.  Coordinate/Contribute to the design and implementation of processes associated with a HT protein production pipeline. 40%
• Support and mentor junior lab members and student workers. 20%
• Coordinate UW cloning, expression-testing and protein production efforts with SCRI and U of Kansas. 15%
• Troubleshoot experimental and equipment problems. 10%
• Participate in SSGCID monthly SLT meetings. 5%
• Participate in SSGCID special focus meetings. Participate in conferences and programmatic meetings as requested.  5%
• Bioinformatics support for target selection. 5%

Supervisory Responsibilities:
Supervisor other Research Scientists and student workers with University of Washington Protein Production Group, UW-PPG

Stakeholders:
NIH funded Structural genomics Program Contract (5 yr) administered in the UW Department of Medicine, Division of Allergy and Infectious Disease, CERID

MINIMUM REQUIREMENTS:

A Master's Degree in Molecular Biology or a related field and at least 4 years of experience

Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.

ADDITIONAL REQUIREMENTS:

• High level of motivation.
• Ability to troubleshoot.
• Good organizational and communication skills and the ability to work as a member of a team is important.
• Mentor or leadership skills/experience.

DESIRED:

• Knowledgeable in molecular biology techniques such as DNA isolation/manipulation, PCR, real time PCR, thermal melts, sequencing, electrophoresis.
• Must have experience with High Throughput methods including 96-well format and multi-channel pipettes.
• Experience in development of biochemical enzyme assays.
• Good organizational skills and the ability to work lead a team of researchers and student assistants.

Application Process:
The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process.  These assessments may include Work Authorization, Cover Letter and/or others.  Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.