Research Lab Specialist Senior, Advanced Genomics Core

Apply Now
How to Apply

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

Summary

The Biomedical Research Core Facilities Advanced Genomics Core is looking for a skilled research technician to join us full time as a Research Laboratory Specialist Senior. The incumbent will assist in developing, deploying and executing protocols to improve single cell/spatial operations in the Advanced Genomics Core.

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.  Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Why Join Michigan Medicine?

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems.  In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

• Excellent medical, dental and vision coverage effective on your very first day
• 2:1 Match on retirement savings

Responsibilities*

Develop, design, and execute methods for spatialomics operations in the Advanced Genomics Core. Optimize existing protocols to improve data quality, identify platform weaknesses and potential problems, and troubleshoot solutions. Research and evaluate new spatial technologies, provide recommendations to core leadership regarding adopting new platforms, onboard new ancillary equipment, and establish novel workflows when implementing new spatialomics assays.

Perform complex spatialomics experiments for using animal and human tissue on the Nanostring GeoMx and 10x Genomics Xenium platforms, expanding to additional related platforms in the future. Responsibilities include sectioning, staining, and imaging frozen or fixed tissue, antibody optimization, assay processing, and instrument maintenance and troubleshooting.

Work directly with spatialomics customers to plan and execute experiments. Educate users regarding technology and equipment capabilities, operations, limitations, and outcomes. Document client requests, communicate sample quality, assay parameters and sample performance.

Required Qualifications*

• Master's degree, Ph.D. preferred, in biochemistry, cell biology, molecular biology, or related biomedical field and 5 to 6 years of research experience with histology, cell or tissue microscopy, fluorescent and stained section imaging, plus basic molecular biology skills.
• A successful candidate must be able to analyze, compare and evaluate various courses of action and make independent decisions on matters of significance, free from immediate direction, within the scope of their responsibilities.
• Proficiency and comfort with computer-based operation is a requirement of the position, including typical office software (MSWord, MS Excel).
• Must be meticulous both at the lab bench and with recordkeeping skills.
• The ability to work independently and as part of a team in a diverse environment while under pressure to produce results in a timely manner is a must.

Desired Qualifications*

Experience in wet-lab immunohistochemistry and in situ hybridization. Experience with tissue preservation (e.g. fixation, cryopreservation) and sectioning including both paraffin embedded and frozen tissue material. Knowledge of methods, materials and equipment used in a laboratory.

Work Locations

Position is located at North Campus Research Complex. Not eligible for remote work.

Additional Information

Michigan Medicine values a culture of diversity, equity, and inclusion. Here at the Biomedical Research Core Facilities (BRCF), our dedication to customer service is inseparable from our commitment to diversity, equity and inclusion. It is central to our mission as an institutional resource to ensure that each member of our community has full opportunity to thrive in our environment, for we believe that diversity is key to individual flourishing, educational excellence and the advancement of knowledge.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.