RESEARCH FELLOW

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Summary

?         This is a posting for a Postdoctoral Research Fellow within the Department of Surgery under principal investigator Donnele Daley. The project will encompass the pathogenesis of pancreatic cancer, specifically focusing on tumor immunology and mechanisms via which the gut microbiome influences tumor progression and response to treatment. 

Responsibilities*

The postdoc will assume mentored responsibility for advancing several studies within 1 or 2 larger projects. The fellow will also be responsible for supervising students, trainees, and volunteers who contribute to these efforts. Additionally, they will assist with:

• Establishing and maintaining mouse colonies.
• Animal surgeries: orthotopic tumor transplantation; tumor monitoring; administration of medication by oral, subcutaneous or intraperitoneal route.
• Animal tissue dissections; tissue fixation and sectioning; immunohistochemical staining and immunofluorescent staining; fluorescent RNA in situ hybridization; confocal microscopy; and image analysis using software such as ImageJ.
• Maintaining primary 2D and 3D cell culture, single cell extraction from tissue, RNA/Protein isolation, qRT-PCR, Western blot, flow cytometry, and gel electrophoresis.
• Analyze data and prepare reports using Microsoft office, GraphPad and Photoshop programs.
• Maintain accurate data logs and overall smooth functioning of laboratory.
• Managing independent projects and taking the lead on writing first author manuscripts.

Required Qualifications*

• PhD in Microbiology, Biological Sciences or Biochemical Sciences to be completed by July 2024.
• Experience in sterile technique for tissue culture, immunohistochemical and immunofluorescence techniques, microscopy, and basic chemical assays.
• Skillset in bioinformatics techniques including single cell sequencing, microbial 16S sequencing, and spacial transcriptomics are favored, but opportunities to learn these bioinformatics techniques will be available.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.