Research Bioinformatician II - Inflammatory Bowel and Immunobiology Research Institute

Requisition # HRC0806656

Everyone’s unique health journey is informed by data. Join us as we translate today's discoveries into tomorrow's medicine!

Cedars-Sinai is home to some of the most advanced biomedical research and training programs in the world, which attracts renowned physician-scientists seeking an unparalleled environment for fostering invention and teamwork.

Dr. Gil Melmed and his clinical research team is seeking a highly motivated Research Bioinformatician II (RB II) to be a part of an exciting opportunity within the Inflammatory Bowel and Immunobiology Research Institute (IBIRI). IBIRI is a multidisciplinary basic, translational and clinical research program devoted to discovering the causes of inflammatory bowel disease with the goal of improved treatment approaches and prevention. To learn more about our lab and institute, please visit:

Gil Y. Melmed, MD - Cedars-Sinai Medical Center Directory

F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute | Cedars-Sinai

The RB II performs general bioinformatics analysis and software support for projects involving omics, and interact with investigators to identify research problems, find appropriate software tools, and recognize national biological databases and online resources for omic data. The RB II will manage omic data including loading and querying data from the database system and public repositories, and transform and merge multilevel omic data into user-friendly formats, assist in development, test, and maintenance of modular software pipelines, provide bioinformatics data analysis, preliminary interpretation of the data, and reports of the results for possible publications. The RB II will demonstrate continuous self-improvement, make effective contributions to the section, adhere to the CSHS compliance plan, code of conduct, and hospital and departmental policies and procedures, and may serve as a preceptor for students.

Primary Job Duties and Responsibilities:

• Provides general bioinformatics analysis support for omic projects and is mainly responsible for data analysis and software compilations including next-generation sequence alignment, polymorphism identification, expression analysis, and visualization tools and browsers.
• Summarizes data analysis results in the form suitable as the basis for the first draft of written reports, and makes preliminary interpretations of the data.
• Develop, test, and maintain modular software pipelines for genome sequencing, assembly, annotation, metagenomic analysis, and genotyping using high-throughput sequencing platforms including 454, Illumina, and Pacific Biosciences
• Manages data including loading and querying data from database systems, downloading omic data from public repositories, and transforming data to the necessary formats
• Familiar with medical and biological terminologies, bioinformatics resources, and national biological databases, Ready to provide solutions for investigator’s problems through data mining and extraction
• Identify, evaluate, and incorporate relevant algorithms and software pipelines by reviewing pertinent literature in bioinformatics and computational biology
• Assists or collaborate in the preparation of grant proposals, publications, and presentations involving omic data
• Helps develop tools and pipelines as necessary to keep pace with rapid advances in sequencing technology.
• Educate others about bioinformatics through mentoring and teaching colleagues, investigators, fellows, and graduate students.

Education:

• Master of Science/Engineering in Computer Science, Bioinformatics, Statistics, or relevant fields (e.g. Biology with strong quantitative training, biostatistics with a concentration in bioinformatics) required.

Experience and Skills:

• Three (3) years in a research environment. Background and work knowledge in algorithms, scientific computing, and machine learning or statistics.
• Familiar with C/C++, Java, Perl, python, and the Unix (Linux) environment.
• Experiences in manipulating, analyzing, and annotating very large genomic (e.g. NGS) data sets both in exploratory and pipelined fashions.
• Ability to apply knowledge of information software and/or hardware to provide solutions and/or support.
• Ability to apply advanced knowledge of science/learning/specialized intellectual instruction to analyze, interpret or make deductions from varying facts or circumstances.

• Working Title: Research Bioinformatician II - Inflammatory Bowel and Immunobiology Research Institute
• Department: Home Dept - Gastroenterology
• Business Entity: Academic / Research
• City: Los Angeles
• Job Category: Academic/Research
• Job Specialty: Bioinformatics
• Position Type: Full-time
• Shift Length: 8 hour shift
• Shift Type: Day

Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law. If you need a reasonable accommodation for any part of the employment process, please contact us by email at [email protected] and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Cedars-Sinai will consider for employment qualified applicants with criminal histories, in accordance with the Los Angeles Fair Chance Initiative for Hiring.

At Cedars-Sinai, we are dedicated to the safety, health and wellbeing of our patients and employees. This includes protecting our patients from communicable diseases, such as influenza (flu) and COVID-19. For this reason, we require that all new employees receive a flu vaccine based on the seasonal availability of flu vaccine (typically during September through April each year) as a condition of employment, and annually thereafter as a condition of continued employment, subject to medical exemption or religious accommodation. For the same reason, you may also be required to receive other vaccines such as COVID-19 as a condition of employment. Cedars-Sinai reserves the right to make modifications to its required list of vaccines as required by law and/or policy.

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