Research Assistant I Lab

04-Dec-2023

Faculty of Arts and Sciences

62395BR

Job Summary

The Wagers laboratory studies the biology and function of adult tissue-specific stem cells, particularly those stem cells that form the skeletal muscle and blood.  Current topics under investigation include regulation of stem cell function in normal tissues and under abnormal conditions such as aging and cancer, and methods for editing stem cell genomes using CRISPR/Cas9 for experimental and therapeutic purposes.  The lab is seeking highly motivated candidates to assist in ongoing experiments that include the development and application of novel CRISPR/Cas9 and adenoassociated virus (AAV) gene transfer technologies, mouse work (colony maintenance, husbandry, genotyping, physiological assessment, tissue harvest, etc.), cell culture, flow cytometry, immunostaining, and bioassays of skeletal muscle and hematopoietic cell function. The assistant will also perform a variety of basic and general lab support and clerical tasks, including ordering and stocking of supplies, maintenance of equipment and preparation and storage of shared reagents. They will also be expected to participate in and present results for regular research group meetings and to contribute to the preparation and presentation of written and oral progress reports, as needed. Work will be performed under the specific direction of the PI, research manager and/or senior lab members, although certain research-related tasks will be performed independently, within the guidelines of and subject to review by the PI and research staff.

Position Description

Performs laboratory experiments utilizing AAVs and CRISPR/Cas9 genome editing complexes, gene engineered mouse models, cell culture, flow cytometry, immunostaining, microscopy, molecular biology and bioassays;

Collects and safeguards project data; keeps detailed, accurate and up-to-date notes detailing experimental design and results;

Under direction, processes, organizes and summarizes data, reporting experiment results in written form and in oral presentations, using a variety of scientific, word processing, spreadsheet and statistical software applications or program platforms;

As a member of a project team, assists in the design and execution of laboratory experiments, techniques, and protocols;

Performs routine logging and/or testing of samples; routine animal husbandry and experimentation, and genotyping

May occasionally instruct others in basic laboratory techniques or procedures;

Performs related laboratory maintenance such as maintaining and cleaning equipment, scheduling repairs, tracking inventory and ordering supplies.

Basic Qualifications

At least one year related work experience (relevant course work may count towards experience).

Additional Qualifications and Skills

Previous undergraduate or post-graduate lab experience, particularly with gene editing systems, animal models and tissue histology will be preferred. Demonstrated abilities in relevant laboratory techniques is also preferred. Exposure to applicable computer technologies, including specific software applications, is encouraged. Appropriate organizational and communications skills required.

Working Conditions

this position is based onsite in Cambridge, MA

Additional Information

This is a one-year, grant-funded position with possibility of renewal based on funding availability.

All formal offers will be made by FAS Human Resources.

We regret that we are unable to provide visa sponsorship

Benefits

We invite you to visit Harvard’s Total Rewards website to learn more about our outstanding benefits package, which may include:

• Paid Time Off: 3-4 weeks of accrued vacation time per year (3 weeks for support staff and 4 weeks for administrative/professional staff), 12 accrued sick days per year, 12.5 holidays plus a Winter Recess in December/January, 3 personal days per year (prorated based on date of hire), and up to 12 weeks of paid leave for new parents who are primary care givers.
• Health and Welfare: Comprehensive medical, dental, and vision benefits, disability and life insurance programs, along with voluntary benefits. Most coverage begins as of your start date.
• Work/Life and Wellness: Child and elder/adult care resources including on campus childcare centers, Employee Assistance Program, and wellness programs related to stress management, nutrition, meditation, and more.
• Retirement: University-funded retirement plan with contributions from 5% to 15% of eligible compensation, based on age and earnings with full vesting after 3 years of service.
• Tuition Assistance Program: Competitive program including $40 per class at the Harvard Extension School and reduced tuition through other participating Harvard graduate schools.
• Tuition Reimbursement: Program that provides 75% to 90% reimbursement up to $5,250 per calendar year for eligible courses taken at other accredited institutions.
• Professional Development: Programs and classes at little or no cost, including through the Harvard Center for Workplace Development and LinkedIn Learning.
• Commuting and Transportation: Various commuter options handled through the Parking Office, including discounted parking, half-priced public transportation passes and pre-tax transit passes, biking benefits, and more.
• Harvard Facilities Access, Discounts and Perks: Access to Harvard athletic and fitness facilities, libraries, campus events, credit union, and more, as well as discounts to various types of services (legal, financial, etc.) and cultural and leisure activities throughout metro-Boston.

Department Office Location

USA - MA - Cambridge

Job Code

403108 Research Assistant I Lab

Department

Stem Cell and Regenerative Biology

Union

55 - Hvd Union Cler & Tech Workers

Pre-Employment Screening

Identity

Schedule

35 hours per week, on-site.

Commitment to Equity, Diversity, Inclusion, and Belonging

Harvard University views equity, diversity, inclusion, and belonging as the pathway to achieving inclusive excellence and fostering a campus culture where everyone can thrive. We strive to create a community that draws upon the widest possible pool of talent to unify excellence and diversity while fully embracing individuals from varied backgrounds, cultures, races, identities, life experiences, perspectives, beliefs, and values.

EEO Statement

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.